Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.62 |
| ▸ | MEN1 | O00255 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.62 |
| ▸ | TSHR | P16473 | 1/20 | 0.62 |
| ▸ | DNM1 | Q05193 | 9/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.48 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.48 |
| ▸ | MMP2 | P08253 | 1/20 | 0.48 |
| ▸ | RAD52 | P43351 | 1/20 | 0.48 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Octanol SCHEMBL29183535 | 1.00 | LMNA (0.62) | LMNAALDH1A1HSD17B10MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL618756 | 1.00 | LMNA (0.62) | LMNAALDH1A1HSD17B10MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL5183982 | 1.00 | LMNA (0.62) | LMNAALDH1A1HSD17B10MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL5604447 | 0.95 | DNM1 (0.58) | LMNAALDH1A1HSD17B10MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL28450551 | 0.95 | DNM1 (0.58) | LMNAALDH1A1HSD17B10MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL28454705 | 0.95 | DNM1 (0.58) | LMNAALDH1A1HSD17B10MEN1KMT2A | |
| Butyl Alcohol SCHEMBL28980165 | 0.95 | DNM1 (0.58) | LMNAALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL4454715 | 0.93 | DNM1 (0.60) | LMNAALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL10622055 | 0.93 | DNM1 (0.60) | LMNAALDH1A1HSD17B10MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL25295106 | 0.91 | DNM1 (0.64) | LMNAALDH1A1HSD17B10MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1802267-A1 | HAIR CONDITIONING COMPOSITION COMPRISING AN ALKYL DIQUATERNIZED AMMONIUM SALT CATIONIC SURFACTANT | The Procter and Gamble Company (US) | 2007-07-04 | — | — | EP | disclosed |
| EP-1799179-A2 | HAIR CONDITIONING COMPOSITION COMPRISING AN ALKYL DIQUATERNIZED AMMONIUM SALT CATIONIC SURFACTANT | The Procter and Gamble Company (US) | 2007-06-27 | — | — | EP | disclosed |
| WO-2006044208-A1 | HAIR CONDITIONING COMPOSITION COMPRISING AN ALKYL DIQUATERNIZED AMMONIUM SALT CATIONIC SURFACTANT | THE PROCTER & GAMBLE COMPANY (US) | 2006-04-27 | — | — | WO | disclosed |
| WO-2006044209-A2 | HAIR CONDITIONING COMPOSITION COMPRISING AN ALKYL DIQUATERNIZED AMMONIUM SALT CATIONIC SURFACTANT | THE PROCTER & GAMBLE COMPANY (US) | 2006-04-27 | — | — | WO | disclosed |
| US-20060078529-A1 | Hair conditioning composition comprising alkyl diquaternized ammonium salt cationic surfactant | PROCTER & GAMBLE COMPANY, THE | 2006-04-13 | — | — | US | disclosed |
| US-20060078528-A1 | Hair conditioning composition comprising tight lamellar gel matrix | THE PROCTER & GAMBLE COMPANGY | 2006-04-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060078528-A1 | Hair conditioning composition comprising tight lamellar gel matrix | DSG1, TRPC5, PCNA | LMNA 1451/4885ALDH1A1 1603/4885HSD17B10 467/4885 |
| US-20060078529-A1 | Hair conditioning composition comprising alkyl diquaternized ammonium salt cationic surfactant | ASIC3, TRPC7, SLC7A1 | LMNA 3704/4885ALDH1A1 1940/4885HSD17B10 402/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.