Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | PTPRZ1 | P23471 | 4/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.50 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | KIF11 | P52732 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | ESR1 | P03372 | 2/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.42 |
| ▸ | KCNK2 | O95069 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | KCNK10 | P57789 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | GMNN | O75496 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phenol SCHEMBL28143703 | 0.83 | TDP1 (0.50) | ALDH1A1KDM4ETDP1PTPRZ1PTPN1 | |
| SCHEMBL10978325 | 0.81 | ALDH1A1 (0.61) | ALDH1A1KDM4ETDP1PTPRZ1PTPN1 | |
| SCHEMBL8712721 | 0.81 | KIF11 (0.59) | ALDH1A1KDM4EKIF11KCNK2NPC1 | |
| SCHEMBL19356939 | 0.77 | NR1H2 (0.42) | ALDH1A1KDM4ETDP1PTPRZ1PTPN1 | |
| SCHEMBL24384354 | 0.76 | NR1H2 (0.52) | ALDH1A1KDM4ETDP1NR1H2LMNA | |
| SCHEMBL7940607 | 0.76 | ALDH1A1 (0.61) | ALDH1A1KDM4ETDP1PTPRZ1PTPN1 | |
| SCHEMBL5919444 | 0.75 | NR1H2 (0.46) | ALDH1A1KDM4ETDP1NR1H2LMNA | |
| SCHEMBL7014603 | 0.74 | ALDH1A1 (0.58) | ALDH1A1KDM4ETDP1PTPRZ1PTPN1 | |
| SCHEMBL2480563 | 0.74 | NR1H2 (0.50) | ALDH1A1KDM4ENR1H2LMNAESR1 | |
| SCHEMBL18686301 | 0.74 | ALDH1A1 (0.41) | ALDH1A1KDM4ETDP1PTPRZ1PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 374 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118165365-A | Preparation method and application of composite heat stabilizer | 万华化学集团股份有限公司 | 2024-06-11 | — | — | CN | claimed |
| CN-116603117-B | Super-hydrophobic drug structure coating with drug release performance and preparation method thereof | 四川大学华西医院 | 2023-10-13 | — | — | CN | claimed |
| CN-116603117-A | Super-hydrophobic drug structure coating with drug release performance and preparation method thereof | 四川大学华西医院 | 2023-08-18 | — | — | CN | claimed |
| WO-2023027630-A9 | A FLOW REACTOR, METHODS OF FABRICATION AND REACTIONS THEREOF | NATIONAL UNIVERSITY OF SINGAPORE (SG) | 2023-07-27 | — | — | WO | claimed |
| WO-2023027630-A2 | A FLOW REACTOR, METHODS OF FABRICATION AND REACTIONS THEREOF | NATIONAL UNIVERSITY OF SINGAPORE (SG) | 2023-03-02 | — | — | WO | claimed |
| CN-114602202-A | Rectifying tower is used in production of P trifluoro methylthio phenol | 江苏永创医药科技股份有限公司 | 2022-06-10 | — | — | CN | claimed |
| CN-107033044-B | A kind of preparation method of pair of trifluoromethylthio phenol | 江苏凌云药业股份有限公司 | 2019-02-12 | — | — | CN | claimed |
| CN-108484458-A | A kind of 3- methyl -4-（4- trifluoromethylthio benzene）The Industrialized synthesis method of oxygroup nitrobenzene | 江苏凌云药业股份有限公司 | 2018-09-04 | — | — | CN | claimed |
| CN-108373434-A | A method of nitre phenylate is synthesized by 2- amino -5- nitrotoleunes | 江苏凌云药业股份有限公司 | 2018-08-07 | — | — | CN | claimed |
| CN-107033044-A | A kind of preparation method to trifluoromethylthio phenol | 江苏凌云药业股份有限公司 | 2017-08-11 | — | — | CN | claimed |
| CN-1370144-A | Aromatic sulfone hydroxamic acid metalloprotease inhibitor | SEARLE & CO (US) | 2002-09-18 | — | — | CN | claimed |
| EP-1230219-A1 | AROMATIC SULFONS HYDROXAMIC ACID METALLOPROTEASE INHIBITOR | G.D. Searle & Co. (US) | 2002-08-14 | — | — | EP | claimed |
| US-20010039287-A1 | AROMATIC SULFONE HYDROXAMIC ACID METALLOPROTEASE INHIBITOR | PHARMACIA CORPORATION | 2001-11-08 | — | — | US | claimed |
| US-20010014688-A1 | AROMATIC SULFONE HYDROXAMIC ACID METALLOPROTEASE INHIBITOR | BARTA THOMAS E (US) | 2001-08-16 | — | — | US | claimed |
| CN-1279669-A | Aromatic sulfone hydroxamic acid metalloprotease inhibitors | SEARLE & CO (US) | 2001-01-10 | — | — | CN | claimed |
| EP-1042290-A1 | AROMATIC SULFONE HYDROXAMIC ACID METALLOPROTEASE INHIBITOR | G.D. SEARLE & CO. (US) | 2000-10-11 | — | — | EP | claimed |
| WO-2000050396-A1 | AROMATIC SULFONE HYDROXAMIC ACID METALLOPROTEASE INHIBITOR | G.D. SEARLE & CO. (US) | 2000-08-31 | — | — | WO | claimed |
| WO-1999025687-A1 | AROMATIC SULFONE HYDROXAMIC ACID METALLOPROTEASE INHIBITOR | G.D. SEARLE & CO. (US) | 1999-05-27 | — | — | WO | claimed |
| EP-0370219-A1 | 4-Trifluor methyl mercaptophenols and their preparation | BAYER AG (DE) | 1990-05-30 | — | — | EP | claimed |
| EP-0093976-B1 | 2,4-DIHALOGENBENZOYL UREAS AND THIOUREAS, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS PESTICIDES | BAYER AG (DE) | 1986-09-10 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010039287-A1 | AROMATIC SULFONE HYDROXAMIC ACID METALLOPROTEASE INHIBITOR | MMP13, MMP9, MMP10 | ALDH1A1 535/4885KDM4E 461/4885TDP1 1409/4885 |
| US-20010014688-A1 | AROMATIC SULFONE HYDROXAMIC ACID METALLOPROTEASE INHIBITOR | MMP13, MMP9, MMP10 | ALDH1A1 535/4885KDM4E 461/4885TDP1 1409/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.