Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | FAAH | O00519 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5195061 | 0.81 | SIGMAR1 (0.49) | MEN1KMT2ASMN1; SMN2L3MBTL1ALDH1A1 | |
| SCHEMBL5192869 | 0.81 | OPRK1 (0.46) | MEN1KMT2ALMNAMAPK1L3MBTL1 | |
| SCHEMBL5193442 | 0.78 | MAPT (0.55) | MEN1KMT2AFAAHSMN1; SMN2MAPT | |
| SCHEMBL5192480 | 0.77 | SIGMAR1 (0.48) | MEN1KMT2ASMN1; SMN2GAAMAPT | |
| SCHEMBL5190010 | 0.76 | POLB (0.60) | KDM4EMEN1KMT2ASMN1; SMN2MAPK1 | |
| SCHEMBL5194086 | 0.76 | FAAH (0.62) | MEN1KMT2AFAAHSMN1; SMN2MAPT | |
| SCHEMBL5193328 | 0.75 | L3MBTL1 (0.49) | KDM4EMEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL5199484 | 0.75 | MAPT (0.51) | MEN1KMT2AFAAHSMN1; SMN2MAPT | |
| SCHEMBL5194848 | 0.74 | OPRK1 (0.46) | KMT2ALMNASMN1; SMN2L3MBTL1GAA | |
| SCHEMBL5210351 | 0.73 | FAAH (0.46) | MEN1KMT2AFAAHLMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0968206-B8 | N-HETEROCYCLIC DERIVATIVES AS NOS INHIBITORS | BERLEX INC (US) | 2007-01-24 | — | — | EP | claimed |
| EP-0968206-A1 | N-HETEROCYCLIC DERIVATIVES AS NOS INHIBITORS | BERLEX LABORATORIES, INC. (US) | 2000-01-05 | — | — | EP | claimed |
| WO-1998037079-A1 | N-HETEROCYCLIC DERIVATIVES AS NOS INHIBITORS | BERLEX LABORATORIES, INC. (US) | 1998-08-27 | — | — | WO | claimed |