SCHEMBL51940

SCHEMBL51940

CCOC(=O)c1cc(N)cc2sc3ccccc3c(=O)c12

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRP O00591 1/20 0.48
GABRD O14764 1/20 0.48
GABRA1 P14867 1/20 0.48
GABRB1 P18505 1/20 0.48
GABRG2 P18507 1/20 0.48
GABRB3 P28472 1/20 0.48
GABRA5 P31644 1/20 0.48
GABRA3 P34903 1/20 0.48
GABRA2 P47869 1/20 0.48
GABRB2 P47870 1/20 0.48
GABRA4 P48169 1/20 0.48
GABRE P78334 1/20 0.48
GABRA6 Q16445 1/20 0.48
GABRG1 Q8N1C3 1/20 0.48
GABRG3 Q99928 1/20 0.48
GABRQ Q9UN88 1/20 0.48
ALDH1A1 P00352 9/20 0.47
MAPT P10636 7/20 0.47
GAA P10253 7/20 0.47
KMT2A Q03164 5/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29501105 1.00 GABRP (0.48) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL29052637 0.89 GABRP (0.40) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL28837371 0.87 GABRP (0.49) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL11166111 0.86 ALDH1A1 (0.50) ALDH1A1MAPTGAAKMT2AMEN1
SCHEMBL28973868 0.86 TP53 (0.46) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL51133 0.86 MAPT (0.48) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL29501104 0.86 MAPT (0.48) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL10801250 0.85 GABRP (0.51) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL51833 0.85 GABRP (0.50) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL9455912 0.85 MAPT (0.49) GABRPGABRDGABRA1GABRB1GABRG2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 671 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11382868-B2 Transdermal UV-curable hydrogel resin, hydrogel curing the same and cataplasm containing the same ICURE PHARMACEUTICAL INC. (KR) 2022-07-12 US claimed
CN-107652222-B Oxime ester photoinitiators 巴斯夫欧洲公司 2021-09-10 CN claimed
US-10919909-B2 Photoinitiated reactions LINTFIELD LIMITED (GB) 2021-02-16 US claimed
US-20190211031-A1 PHOTOINITIATED REACTIONS LINTFIELD LIMITED (GB) 2019-07-11 US claimed
US-20190046463-A1 ULTRAVIOLET-HARDENING HYDROGEL RESIN AND HYDROGEL FOR TRANSDERMAL ADMINISTRATION, AND CATAPLASM AGENT CONTAINING SAME ICURE PHARMACEUTICAL INC. (KR) 2019-02-14 US claimed
EP-3415141-A1 ULTRAVIOLET-HARDENING HYDROGEL RESIN AND HYDROGEL FOR TRANSDERMAL ADMINISTRATION, AND CATAPLASM AGENT CONTAINING SAME Icure Pharmaceutical Inc. (KR) 2018-12-19 EP claimed
EP-2190887-B1 PHOTOINITIATORS FOR ENERGY CURING LAMBERTI SPA (IT) 2011-05-04 EP claimed
US-20100196826-A1 Photoinitiators for Energy Curing LAMBERTI SPA (IT) 2010-08-05 US claimed
EP-2190887-A1 PHOTOINITIATORS FOR ENERGY CURING Lamberti Spa (IT) 2010-06-02 EP claimed
US-20100093883-A1 Hydroxamic Esters as Photoinitiators LAMBERTI SPA (IT) 2010-04-15 US claimed
CN-101646564-A Hydroxamates as photoinitiators LAMBERTI SPA IT 2010-02-10 CN claimed
EP-2121323-A1 HYDROXAMIC ESTERS AS PHOTOINITIATORS Lamberti Spa (IT) 2009-11-25 EP claimed
WO-2009037130-A1 PHOTOINITIATORS FOR ENERGY CURING LAMBERTI SPA (IT) 2009-03-26 WO claimed
WO-2008104436-A1 HYDROXAMIC ESTERS AS PHOTOINITIATORS LAMBERTI SPA (IT) 2008-09-04 WO claimed
EP-4555025-B1 PHOTOINITIATOR PACKAGE COMPRISING SPECIALISED BISACYLPHOSPHINE OXIDE PHOTOINITIATORS, FURTHER ACYLPHOSPHINE OXIDE PHOTOINITIATORS AND OPTICAL BRIGHTENER SENSITIZERS IGM GROUP B V (NL) 2026-05-13 EP disclosed
EP-3902878-B1 PHOTOINITIATORS IGM RESINS ITALIA SRL (IT) 2026-05-06 EP disclosed
EP-4534614-B1 PHOTOINITIATOR PACKAGE COMPRISING SPECIALISED BISACYLPHOSPHINE OXIDE PHOTOINITIATORS, FURTHER ACYLPHOSPHINE OXIDE PHOTOINITIATORS AND OPTICAL BRIGHTENER SENSITIZERS IGM GROUP B V (NL) 2026-04-15 EP disclosed
EP-0138754-B1 PHOTOCURABLE COMPOSITIONS CIBA-GEIGY AG (CH) 1988-05-25 EP disclosed
EP-0138754-A2 Photocurable compositions CIBA-GEIGY AG (CH) 1985-04-24 EP disclosed
US-4385182-A SENSITIZERS OR PHOTOINITIATORS CIBA-GEIGY CORPORATION (US) 1983-05-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10919909-B2 Photoinitiated reactions KMO, DECR1, PPOX GABRP 2387/4885GABRD 1484/4885GABRA1 1950/4885
US-20100196826-A1 Photoinitiators for Energy Curing PPOX, ECPAS, PTGES GABRP 647/4885GABRD 1147/4885GABRA1 558/4885
US-20190211031-A1 PHOTOINITIATED REACTIONS DOHH, PAH, DBH GABRP 1961/4885GABRD 2392/4885GABRA1 2434/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.