Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | ITGB3 | P05106 | 7/20 | 0.42 |
| ▸ | ITGA2B | P08514 | 7/20 | 0.42 |
| ▸ | ITGB1 | P05556 | 2/20 | 0.42 |
| ▸ | ITGA4 | P13612 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | FPR2 | P25090 | 1/20 | 0.41 |
| ▸ | ACE | P12821 | 1/20 | 0.40 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5499791 | 0.87 | LDHA (0.54) | ALDH1A1ITGB3ITGA2BITGB1ITGA4 | |
| SCHEMBL7862434 | 0.85 | ALDH1A1 (0.50) | ALDH1A1TSHRALOX15 | |
| SCHEMBL2320402 | 0.81 | FPR2 (0.54) | ITGB3ITGA2BITGB1ITGA4FPR2 | |
| SCHEMBL8485515 | 0.81 | FPR2 (0.54) | ITGB3ITGA2BITGB1ITGA4FPR2 | |
| SCHEMBL5262273 | 0.81 | ITGB3 (0.44) | ITGB3ITGA2BITGB1ITGA4ACE | |
| SCHEMBL5199846 | 0.81 | ALDH1A1 (0.41) | ALDH1A1LMNATSHRNPSR1L3MBTL1 | |
| SCHEMBL844471 | 0.80 | ITGB3 (0.58) | ITGB3ITGA2BITGB1ITGA4FPR2 | |
| SCHEMBL2185240 | 0.80 | ITGB3 (0.58) | ITGB3ITGA2BITGB1ITGA4FPR2 | |
| SCHEMBL7758997 | 0.80 | ITGB3 (0.58) | ITGB3ITGA2BITGB1ITGA4FPR2 | |
| SCHEMBL5502788 | 0.79 | FPR2 (0.52) | ALDH1A1ITGB3ITGA2BALOX15FPR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1576179-A4 | METHODS AND COMPOSITIONS FOR INDUCING APOPTOSIS IN CANCER CELLS | IRM LLC (BM) | 2007-06-06 | — | — | EP | disclosed |
| EP-1576179-A2 | METHODS AND COMPOSITIONS FOR INDUCING APOPTOSIS IN CANCER CELLS | IRM LLC (BM) | 2005-09-21 | — | — | EP | disclosed |
| WO-2004050895-A2 | METHODS AND COMPOSITIONS FOR INDUCING APOPTOSIS IN CANCER CELLS | IRM LLC (BM) | 2004-06-17 | — | — | WO | disclosed |