Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 10/20 | 0.44 |
| ▸ | ITGA2B | P08514 | 9/20 | 0.44 |
| ▸ | ITGB1 | P05556 | 2/20 | 0.44 |
| ▸ | ITGA4 | P13612 | 2/20 | 0.44 |
| ▸ | ACE | P12821 | 2/20 | 0.42 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.42 |
| ▸ | CTSK | P43235 | 2/20 | 0.41 |
| ▸ | CTSL | P07711 | 1/20 | 0.41 |
| ▸ | CTSS | P25774 | 1/20 | 0.41 |
| ▸ | ITGAV | P06756 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5085119 | 0.88 | CTSK (0.50) | ITGB3ITGA2BACEACE2CTSK | |
| SCHEMBL3663289 | 0.87 | ACE (0.51) | ITGB3ITGA2BITGB1ITGA4ACE | |
| SCHEMBL16680262 | 0.84 | ACE (0.51) | ITGB3ITGA2BITGB1ITGA4ACE | |
| SCHEMBL7758997 | 0.83 | ITGB3 (0.58) | ITGB3ITGA2BITGB1ITGA4ACE | |
| SCHEMBL844471 | 0.83 | ITGB3 (0.58) | ITGB3ITGA2BITGB1ITGA4ACE | |
| SCHEMBL2185240 | 0.83 | ITGB3 (0.58) | ITGB3ITGA2BITGB1ITGA4ACE | |
| SCHEMBL17578028 | 0.82 | CTSS (0.42) | ITGB1ITGA4CTSKCTSLCTSS | |
| SCHEMBL5198519 | 0.81 | ALDH1A1 (0.45) | ITGB3ITGA2BITGB1ITGA4ACE | |
| SCHEMBL17578191 | 0.81 | CYP1A2 (0.39) | ITGB1ITGA4ACEACE2 | |
| SCHEMBL16679848 | 0.81 | ITGB3 (0.47) | ITGB3ITGA2BITGB1ITGA4ACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3619205-A1 | INHIBITORS OF HUMAN IMMUNODEFICIENCY VIRUS REPLICATION | VIIV Healthcare UK (No.5) Limited (GB) | 2020-03-11 | — | — | EP | disclosed |
| WO-2018203235-A1 | INHIBITORS OF HUMAN IMMUNODEFICIENCY VIRUS REPLICATION | VIIV Healthcare UK (No.5) Limited (GB) | 2018-11-08 | — | — | WO | disclosed |
| EP-1789388-A2 | METHODS OF TREATMENT OF AMYLOIDOSIS USING SUBSTITUTED ETHANOLCYCLICAMINE ASPARTYL PROTEASE INHIBITORS | Elan Pharmaceuticals, Inc. (US) | 2007-05-30 | — | — | EP | disclosed |
| WO-2006026532-A2 | METHODS OF TREATMENT OF AMYLOIDOSIS USING SUBSTITUTED ETHANOLCYCLICAMINE ASPARTYL PROTEASE INHIBITORS | ELAN PHARMACEUTICALS, INC. (US) | 2006-03-09 | — | — | WO | disclosed |