Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | STAT3 | P40763 | 1/20 | 0.46 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | HK1 | P19367 | 1/20 | 0.42 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | SRC | P12931 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1906715 | 0.74 | POLB (0.55) | ALDH1A1SMN1; SMN2GAAKDM4ELMNA | |
| SCHEMBL9022740 | 0.73 | MAOA (0.51) | ALDH1A1MAPK1STAT3CYP11B2SMN1; SMN2 | |
| SCHEMBL28988803 | 0.73 | CYP11B2 (0.73) | ALDH1A1MAPK1CYP11B2SMN1; SMN2TDP1 | |
| SCHEMBL3373253 | 0.70 | P2RX4 (0.47) | ALDH1A1SMN1; SMN2GAAKDM4EGLA | |
| SCHEMBL6142952 | 0.69 | HPGD (0.57) | ALDH1A1MAPK1SMN1; SMN2KMT2AKDM4E | |
| SCHEMBL9023167 | 0.68 | PGR (0.45) | ALDH1A1MAPK1STAT3CYP11B2SMN1; SMN2 | |
| SCHEMBL27796334 | 0.68 | ALDH1A1 (0.43) | ALDH1A1MAPK1STAT3SMN1; SMN2TDP1 | |
| SCHEMBL27620887 | 0.67 | EGFR (0.45) | ALDH1A1MEN1GAAKMT2AKDM4E | |
| SCHEMBL1039147 | 0.67 | ALDH1A1 (0.49) | ALDH1A1MAPK1STAT3CYP11B2SMN1; SMN2 | |
| SCHEMBL9022441 | 0.66 | MAOA (0.54) | ALDH1A1MAPK1CYP11B2TDP1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1829872-B1 | PROCESSES FOR PRODUCTION OF INDOLE COMPOUNDS | NISSAN CHEMICAL IND LTD (JP) | 2015-07-29 | — | — | EP | disclosed |
| EP-1829872-A1 | PROCESSES FOR PRODUCTION OF INDOLE COMPOUNDS | Nissan Chemical Industries, Ltd. (JP) | 2007-09-05 | — | — | EP | disclosed |