Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCA | P17252 | 1/20 | 0.46 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.46 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.45 |
| ▸ | HTR2C | P28335 | 2/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | NCF1 | P14598 | 2/20 | 0.42 |
| ▸ | GABRP | O00591 | 1/20 | 0.42 |
| ▸ | GABRD | O14764 | 1/20 | 0.42 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.42 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.42 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.42 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.42 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.42 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.42 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2130721 | 0.87 | GABRP (0.50) | KDM4EGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL2132966 | 0.86 | GABRP (0.49) | KDM4EGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL30572289 | 0.82 | IKBKB (0.45) | PRKCAPRKCQPRKCDKDM4ECYP3A4 | |
| SCHEMBL5205003 | 0.80 | PRKCQ (0.46) | PRKCQKDM4EHSD17B10HRH4HRH3 | |
| SCHEMBL2130484 | 0.77 | PKM (0.53) | KDM4EHSD17B10GABRPGABRDGABRA1 | |
| SCHEMBL30612354 | 0.77 | KDM4E (0.46) | PRKCAPRKCQPRKCDKDM4ECYP3A4 | |
| SCHEMBL12469440 | 0.75 | PRKCA (0.62) | PRKCAPRKCQPRKCDKDM4ECYP3A4 | |
| SCHEMBL2220368 | 0.75 | ADRB1 (0.54) | KDM4EHSD17B10ADRB1USP2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL2489674 | 0.74 | ADRB1 (0.52) | KDM4EHSD17B10ADRB1USP2ALDH1A1 | |
| SCHEMBL16338929 | 0.74 | PTGER4 (0.43) | KDM4ECYP3A4HSD17B10HRH3GABRP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1307444-B1 | SUBSTITUTED HETEROCYCLIC AMIDES | LILLY CO ELI (US) | 2007-10-03 | — | — | EP | claimed |