Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCQ | Q04759 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | PIM2 | Q9P1W9 | 3/20 | 0.45 |
| ▸ | PIM1 | P11309 | 2/20 | 0.45 |
| ▸ | HTR3A | P46098 | 5/20 | 0.44 |
| ▸ | HTR3E | A5X5Y0 | 4/20 | 0.44 |
| ▸ | HTR3B | O95264 | 4/20 | 0.44 |
| ▸ | HTR3D | Q70Z44 | 4/20 | 0.44 |
| ▸ | HTR3C | Q8WXA8 | 4/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.44 |
| ▸ | PARP1 | P09874 | 1/20 | 0.44 |
| ▸ | GABRP | O00591 | 1/20 | 0.43 |
| ▸ | GABRD | O14764 | 1/20 | 0.43 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.43 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.43 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2130721 | 0.88 | GABRP (0.50) | KDM4EALDH1A1PARP1GABRPGABRD | |
| SCHEMBL2132966 | 0.87 | GABRP (0.49) | KDM4EALDH1A1PARP1GABRPGABRD | |
| SCHEMBL5205369 | 0.80 | PRKCA (0.46) | PRKCQKDM4EALDH1A1PIM2HTR3A | |
| SCHEMBL20632511 | 0.79 | HTR3A (0.51) | KDM4EALDH1A1HTR3AHTR3EHTR3B | |
| SCHEMBL2130484 | 0.78 | PKM (0.53) | KDM4EALDH1A1HSD17B10PKMGABRP | |
| SCHEMBL12984367 | 0.77 | GABRP (0.42) | KDM4EALDH1A1PIM1GABRPGABRD | |
| SCHEMBL1330727 | 0.75 | HSD11B1 (0.52) | HRH4 | |
| SCHEMBL5207636 | 0.73 | RAB9A (0.53) | KDM4EALDH1A1HSD17B10HRH3HPGD | |
| SCHEMBL12984777 | 0.73 | GRIN2D (0.52) | ALDH1A1HRH4 | |
| SCHEMBL21262265 | 0.71 | KDM4E (0.45) | PRKCQKDM4EALDH1A1PIM2PIM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1307444-B1 | SUBSTITUTED HETEROCYCLIC AMIDES | LILLY CO ELI (US) | 2007-10-03 | — | — | EP | claimed |