Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LOX | P28300 | 2/20 | 0.36 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL5201682 | 0.92 | ALDH1A1 (0.40) | KMT2ACACNA1BHPGDALOX15TDP1 | |
| Trifluoroacetic Acid SCHEMBL5202243 | 0.89 | EPHX2 (0.36) | CACNA1BTDP1ALDH1A1LOXLOXL2 | |
| Trifluoroacetic Acid SCHEMBL5201746 | 0.88 | CACNA1B (0.36) | KMT2ACACNA1BALDH1A1LOXLOXL2 | |
| Trifluoroacetic Acid SCHEMBL5208477 | 0.88 | ALDH1A1 (0.37) | KMT2ACACNA1BALDH1A1LOXLOXL2 | |
| Trifluoroacetic Acid SCHEMBL5202153 | 0.88 | TSPO (0.41) | SCN9AKMT2AHPGDALDH1A1MEN1 | |
| Trifluoroacetic Acid SCHEMBL5204751 | 0.88 | TPSAB1 (0.35) | KMT2ACACNA1BTDP1ALDH1A1LOX | |
| Trifluoroacetic Acid SCHEMBL5207958 | 0.87 | SMN1; SMN2 (0.47) | KMT2AHPGDTDP1ALDH1A1MEN1 | |
| Trifluoroacetic Acid SCHEMBL5208348 | 0.87 | RAB9A (0.37) | SCN9AKMT2ACACNA1BLOXLOXL2 | |
| Trifluoroacetic Acid SCHEMBL5207856 | 0.86 | KMT2A (0.37) | KMT2AHPGDALOX15TDP1ALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL5207332 | 0.85 | TPSAB1 (0.44) | KMT2AALDH1A1LOXLOXL2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7160887-B1 | Aromatic amine derivatives, their production and use | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-01-09 | — | — | US | disclosed |
| EP-1123918-B1 | AROMATIC AMINE DERIVATIVES, PROCESS FOR THE PREPARATION THEREOF AND AGENTS CONTAINING THE SAME | TAKEDA PHARMACEUTICAL (JP) | 2005-03-09 | — | — | EP | disclosed |
| EP-1123918-A1 | AROMATIC AMINE DERIVATIVES, PROCESS FOR THE PREPARATION THEREOF AND AGENTS CONTAINING THE SAME | Takeda Chemical Industries, Ltd. (JP) | 2001-08-16 | — | — | EP | disclosed |