Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 6/20 | 0.44 |
| ▸ | OPRD1 | P41143 | 4/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.42 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.42 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.42 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.42 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | DRD1 | P21728 | 1/20 | 0.42 |
| ▸ | HTR7 | P34969 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | KYNU | Q16719 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5206391 | 1.00 | OPRK1 (0.44) | OPRK1OPRD1HIF1AADRB2ADRB1 | |
| SCHEMBL16783311 | 0.81 | KYNU (0.45) | HIF1AADRB2ADRB1HTR1AADRA2A | |
| SCHEMBL5502273 | 0.80 | TAAR1 (0.41) | OPRK1SLC6A3 | |
| SCHEMBL4823405 | 0.78 | ALDH1A1 (0.47) | OPRK1HIF1ASLC6A3KYNU | |
| SCHEMBL2849432 | 0.77 | KYNU (0.48) | OPRK1OPRD1HIF1AADRB2ADRB1 | |
| SCHEMBL23607759 | 0.76 | LIPG (0.38) | HIF1A | |
| SCHEMBL4595940 | 0.75 | HIF1A (0.51) | OPRK1OPRD1HIF1AADRB2ADRB1 | |
| SCHEMBL2808694 | 0.74 | LMNA (0.50) | OPRK1HIF1AADRB2ADRB1HTR1A | |
| SCHEMBL11162583 | 0.74 | HIF1A (0.45) | OPRK1OPRD1HIF1AADRB2ADRB1 | |
| SCHEMBL6176429 | 0.74 | LMNA (0.50) | OPRK1HIF1AADRB2ADRB1HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7160887-B1 | Aromatic amine derivatives, their production and use | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-01-09 | — | — | US | disclosed |