Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 3/20 | 0.54 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.45 |
| ▸ | NAMPT | P43490 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 3/20 | 0.42 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 6/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | CCR3 | P51677 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 5/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | STAT1 | P42224 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5191220 | 0.84 | FAAH (0.51) | FAAHTP53NPC1POLBTDP1 | |
| SCHEMBL5194091 | 0.81 | FAAH (0.53) | FAAHNPC1TDP1CCR3RAB9A | |
| SCHEMBL5195403 | 0.81 | HPGD (0.42) | NAMPTTP53MAPK14NPC1RAB9A | |
| SCHEMBL5193432 | 0.76 | MAPT (0.50) | FAAHNAMPTTP53CCR3RAB9A | |
| SCHEMBL5193648 | 0.75 | POLB (0.53) | FAAHCXCR4TP53NPC1POLB | |
| SCHEMBL5193739 | 0.73 | PKM (0.56) | POLBTDP1CCR3RAB9ASMN1; SMN2 | |
| SCHEMBL5193499 | 0.73 | FAAH (0.52) | FAAHNAMPTCCR3SMN1; SMN2MEN1 | |
| SCHEMBL5191591 | 0.73 | TP53 (0.53) | TP53NPC1POLBTDP1RAB9A | |
| SCHEMBL5210355 | 0.71 | CCR2 (0.50) | TP53NPC1CCR3RAB9ALMNA | |
| SCHEMBL5192584 | 0.71 | CCR3 (0.51) | FAAHNAMPTCCR3SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0968206-B8 | N-HETEROCYCLIC DERIVATIVES AS NOS INHIBITORS | BERLEX INC (US) | 2007-01-24 | — | — | EP | claimed |
| EP-0968206-A1 | N-HETEROCYCLIC DERIVATIVES AS NOS INHIBITORS | BERLEX LABORATORIES, INC. (US) | 2000-01-05 | — | — | EP | claimed |
| WO-1998037079-A1 | N-HETEROCYCLIC DERIVATIVES AS NOS INHIBITORS | BERLEX LABORATORIES, INC. (US) | 1998-08-27 | — | — | WO | claimed |