SCHEMBL5212224

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5215720	0.95	MAPT (0.40)	MAPTALDH1A1GFERPOLBTNKS
	SCHEMBL5211421	0.93	TNKS (0.42)	MAPTALDH1A1POLBTNKSRXFP1
	SCHEMBL5215192	0.91	PIN1 (0.43)	MAPTPOLBTNKSCNR1
	SCHEMBL5207954	0.89	RAB9A (0.42)	MAPTALDH1A1POLBTNKSRXFP1
	SCHEMBL5208205	0.89	TP53 (0.42)	MAPTALDH1A1POLBTNKSRXFP1
	SCHEMBL5212283	0.89	NUDT1 (0.40)	MAPTALDH1A1POLBTNKSRXFP1
	SCHEMBL5213638	0.89	ENPP2 (0.42)	MAPTALDH1A1SMN1; SMN2THRBL3MBTL1
	SCHEMBL5212587	0.89	THRB (0.50)	MAPTALDH1A1RXFP1SMN1; SMN2THRB
	SCHEMBL5211745	0.89	MAPT (0.41)	MAPTALDH1A1POLBTNKSRXFP1
	SCHEMBL5211475	0.89	MAPT (0.41)	MAPTALDH1A1POLBTNKSRXFP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.