Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TXNRD1 | Q16881 | 6/20 | 0.48 |
| ▸ | SMPD3 | Q9NY59 | 6/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.43 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.43 |
| ▸ | OGFRL1 | Q5TC84 | 2/20 | 0.43 |
| ▸ | AKT1 | P31749 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | SUV39H2 | Q9H5I1 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5219253 | 0.85 | TXNRD1 (0.47) | TXNRD1ALDH1A1OPRK1 | |
| SCHEMBL2270852 | 0.82 | SMPD3 (0.48) | SMPD3OPRK1OPRM1OPRD1OGFRL1 | |
| SCHEMBL2689490 | 0.79 | TDP1 (0.52) | TXNRD1ALDH1A1 | |
| SCHEMBL5754970 | 0.77 | TXNRD1 (0.48) | TXNRD1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL5220902 | 0.76 | TXNRD1 (0.49) | TXNRD1ALDH1A1 | |
| SCHEMBL5752857 | 0.75 | ALDH1A1 (0.64) | TXNRD1ALDH1A1 | |
| SCHEMBL2421463 | 0.75 | ALDH1A1 (0.64) | TXNRD1ALDH1A1 | |
| SCHEMBL3281560 | 0.75 | OPRK1 (0.40) | TXNRD1ALDH1A1OPRK1 | |
| SCHEMBL6509373 | 0.74 | TXNRD1 (0.47) | TXNRD1ALDH1A1 | |
| SCHEMBL5385948 | 0.73 | HPGD (0.54) | SMPD3ALDH1A1AKT1SUV39H2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1336606-B1 | 6-Alkoxy-2,3-diaminopyridine couplers for dyeing keratin fibers | OREAL (FR) | 2006-12-27 | — | — | EP | disclosed |
| US-6916345-B2 | 6-alkoxy-2,3-diaminopyridine couplers for dyeing keratin fibres | L'OREAL S.A. (FR) | 2005-07-12 | — | — | US | disclosed |
| US-20030226216-A1 | Novel 6-alkoxy-2,3-diaminopyridine couplers for dyeing keratin fibres | L'OREAL S.A. (FR) | 2003-12-11 | — | — | US | disclosed |
| EP-1336606-A1 | 6-Alkoxy-2,3-diaminopyridine couplers for dying keratin fibers | L'OREAL (FR) | 2003-08-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030226216-A1 | Novel 6-alkoxy-2,3-diaminopyridine couplers for dyeing keratin fibres | KRT18, DSP, DPYD | TXNRD1 1135/4885SMPD3 2822/4885ALDH1A1 170/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.