SCHEMBL5220000

SCHEMBL5220000

NCCOCCOCCOCCON

nearest known ligand 0.47

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ODC1 P11926 1/20 0.47
ADRB2 P07550 1/20 0.32
ADRB1 P08588 1/20 0.32
ADRB3 P13945 1/20 0.32
MEN1 O00255 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13221671 1.00 ODC1 (0.47) ODC1ADRB2ADRB1ADRB3MEN1
SCHEMBL2127510 1.00
SCHEMBL24500071 1.00 ODC1 (0.47) ODC1ADRB2ADRB1ADRB3MEN1
SCHEMBL16329755 1.00 ODC1 (0.47) ODC1ADRB2ADRB1ADRB3MEN1
SCHEMBL8470775 0.87 MEN1 (0.55) ODC1MEN1KMT2A
SCHEMBL11885390 0.86 ODC1 (0.41) ODC1ADRB2ADRB1ADRB3MEN1
SCHEMBL19107454 0.86 MEN1 (0.38) ODC1MEN1KMT2A
SCHEMBL14745208 0.86 MEN1 (0.38) ODC1MEN1KMT2A
SCHEMBL2639323 0.86 MEN1 (0.38) ODC1MEN1KMT2A
Aminooxyethoxyethoxyethylhydroxylamine SCHEMBL43069 0.86 ODC1 (0.41) ODC1ADRB2ADRB1ADRB3MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024086767-A2 GLYCAN CONJUGATE COMPOSITIONS AND METHODS GANNA BIO, INC. (US) 2024-04-25 WO disclosed
US-20230323344-A1 POLYNUCLEOTIDES CONTAINING A MORPHOLINO LINKER ARES CAPITAL CORPORATION, AS AGENT 2023-10-12 US disclosed
US-11766481-B2 Glycan modified short interfering RNA GANNA BIO, INC. (US) 2023-09-26 US disclosed
EP-4101930-A1 POLYNUCLEOTIDES CONTAINING A STABILIZING TAIL REGION ModernaTX, Inc. (US) 2022-12-14 EP disclosed
US-20220387607-A1 GLYCAN MODIFIED NUCLEIC ACIDS, METHODS OF PREPARATION, AND THERAPEUTIC USES NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2022-12-08 US disclosed
EP-3350333-B1 POLYNUCLEOTIDES CONTAINING A STABILIZING TAIL REGION MODERNATX INC (US) 2021-10-27 EP disclosed
US-20210283139-A1 BIFUNCTIONAL MOLECULES FOR TARGETING UCHL5 AMPHISTA THERAPEUTICS LIMITED (GB) 2021-09-16 US disclosed
US-20190078087-A1 POLYNUCLEOTIDES CONTAINING A MORPHOLINO LINKER ARES CAPITAL CORPORATION, AS AGENT 2019-03-14 US disclosed
US-10017460-B2 Compounds for promoting liposomal and cellular adhesion and compositions and methods of use thereof ORGANOLINX CORP. (CA) 2018-07-10 US disclosed
US-10017460-B2 Compounds for promoting liposomal and cellular adhesion and compositions and methods of use thereof ORGANOLINX CORP. (CA) 2018-07-10 US disclosed
WO-2017049286-A1 POLYNUCLEOTIDES CONTAINING A MORPHOLINO LINKER MODERNA THERAPEUTICS, INC. (US) 2017-03-23 WO disclosed
US-20160130216-A1 COMPOUNDS FOR PROMOTING LIPOSOMAL AND CELLULAR ADHESION AND COMPOSITIONS AND METHODS OF USE THEREOF ORGANOLINX CORP. (CA) 2016-05-12 US disclosed
US-20160130216-A1 COMPOUNDS FOR PROMOTING LIPOSOMAL AND CELLULAR ADHESION AND COMPOSITIONS AND METHODS OF USE THEREOF ORGANOLINX CORP. (CA) 2016-05-12 US disclosed
US-20160130216-A1 COMPOUNDS FOR PROMOTING LIPOSOMAL AND CELLULAR ADHESION AND COMPOSITIONS AND METHODS OF USE THEREOF ORGANOLINX CORP. (CA) 2016-05-12 US disclosed
WO-2014197991-A1 COMPOUNDS FOR PROMOTING LIPOSOMAL AND CELLULAR ADHESION AND COMPOSITIONS AND METHODS OF USE THEREOF YOUSAF MUHAMMAD (CA) 2014-12-18 WO disclosed
US-20070286783-A1 METHOD OF DEACIDIZING A GASEOUS EFFLUENT WITH EXTRACTION OF THE PRODUCTS TO BE REGENERATED CARRETTE PIERRE-LOUIS 2007-12-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11766481-B2 Glycan modified short interfering RNA SNRPE, FUT6, ALG8 ODC1 2742/4885ADRB2 4796/4885ADRB1 4737/4885
US-20210283139-A1 BIFUNCTIONAL MOLECULES FOR TARGETING UCHL5 UCHL5, UCHL3, UCHL1 ODC1 3564/4885ADRB2 4416/4885ADRB1 4317/4885
US-10017460-B2 Compounds for promoting liposomal and cellular adhesion and compositions and methods of use thereof LPAR2, SGMS2, PHOSPHO1 ODC1 3068/4885ADRB2 1689/4885ADRB1 2912/4885
US-20220387607-A1 GLYCAN MODIFIED NUCLEIC ACIDS, METHODS OF PREPARATION, AND THERAPEUTIC USES NSUN3, RNGTT, SIGLEC7 ODC1 3381/4885ADRB2 4830/4885ADRB1 4801/4885
US-20160130216-A1 COMPOUNDS FOR PROMOTING LIPOSOMAL AND CELLULAR ADHESION AND COMPOSITIONS AND METHODS OF USE THEREOF LPAR2, SGMS2, PHOSPHO1 ODC1 3068/4885ADRB2 1689/4885ADRB1 2912/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.