Aminooxyethoxyethoxyethylhydroxylamine

Aminooxyethoxyethoxyethylhydroxylamine

SCHEMBL43069

NOCCOCCOCCON

nearest known ligand 0.41

Full drug profile on Sugi Atlas →

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ODC1 P11926 1/20 0.41
ADRB2 P07550 1/20 0.39
ADRB1 P08588 1/20 0.39
ADRB3 P13945 1/20 0.39
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38
TSHR P16473 1/20 0.31
MAPK1 P28482 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL667646 1.00
SCHEMBL11885390 1.00 ODC1 (0.41) ODC1ADRB2ADRB1ADRB3MEN1
SCHEMBL758346 1.00 ODC1 (0.41) ODC1ADRB2ADRB1ADRB3MEN1
SCHEMBL10076924 1.00 ODC1 (0.41) ODC1ADRB2ADRB1ADRB3MEN1
Water SCHEMBL20496293 0.96 ODC1 (0.39) ODC1ADRB2ADRB1ADRB3MEN1
SCHEMBL22169531 0.89 ODC1 (0.42) ODC1ADRB2ADRB1ADRB3MEN1
SCHEMBL24500071 0.86 ODC1 (0.47) ODC1ADRB2ADRB1ADRB3MEN1
SCHEMBL16329755 0.86 ODC1 (0.47) ODC1ADRB2ADRB1ADRB3MEN1
SCHEMBL13221671 0.86 ODC1 (0.47) ODC1ADRB2ADRB1ADRB3MEN1
SCHEMBL2127510 0.86

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 113 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160355859-A1 TRANSGLUTAMINASE MEDIATED CONJUGATION OF PEPTIDES NOVO NORDISK A/S (DK) 2016-12-08 US claimed
US-9505900-B2 Method for producing xerogel composites BASF SE (DE) 2016-11-29 US claimed
CN-103215328-A Transglutaminase mediated conjugation of peptides NOVO NORDISK AS 2013-07-24 CN claimed
EP-2033662-B1 Transglutaminase mediated conjugation of peptides NOVO NORDISK HEALTHCARE AG (CH) 2012-10-17 EP claimed
EP-2368579-A1 Transglutaminase mediated conjugation of peptides Novo Nordisk Health Care AG (CH) 2011-09-28 EP claimed
US-20100009917-A1 Modulating Enzymatic Processes by Addition of Diolcontaining Substances NOVO NORDISK HEALTH CARE AG (CH) 2010-01-14 US claimed
US-20090264366-A1 Transglutaminase Mediated Conjugation of Peptides NOVO NORDISK HEALTHCARE AG (CH) 2009-10-22 US claimed
EP-2033662-A1 Transglutaminase mediated conjugation of peptides Novo Nordisk Health Care AG (CH) 2009-03-11 EP claimed
US-20070105770-A1 Transglutaminase mediated conjugation of peptides NOVO NORDISK A/S (DK) 2007-05-10 US claimed
EP-3838927-B1 CROSS-LINKED HYALURONIC ACID AND USE THEREOF FOR LIMITING THE RECURRENCE OF A TUMOUR COMMISSARIAT ENERGIE ATOMIQUE (FR) 2024-10-09 EP disclosed
US-20230364262-A1 VIA CYCLOADDITION BILATERALLY FUNCTIONALIZED ANTIBODIES SYNAFFIX B.V. (NL) 2023-11-16 US disclosed
US-20230190951-A1 CONJUGATES OF ANTIBODIES AN IMMUNE CELL ENGAGERS SYNAFFIX B.V. (NL) 2023-06-22 US disclosed
US-20230114866-A1 VIA CYCLOADDITION BILATERALLY FUNCTIONALIZED ANTIBODIES SYNAFFIX B.V. (NL) 2023-04-13 US disclosed
WO-2021144313-A1 VIA CYCLOADDITION BILATERALLY FUNCTIONALIZED ANTIBODIES SYNAFFIX B.V. (NL) 2021-07-22 WO disclosed
EP-1183230-A1 VALENCY PLATFORM MOLECULES COMPRISING AMINOOXY GROUPS LA JOLLA PHARMACEUTICAL (US) 2002-03-06 EP disclosed
EP-1092027-A1 THERAPEUTIC AND DIAGNOSTIC DOMAIN 1 BETA 2 GP1 POLYPEPTIDES AND METHODS OF USING SAME LA JOLLA PHARMACEUTICAL COMPANY (CA) 2001-04-18 EP disclosed
WO-2000075105-A1 VALENCY PLATFORM MOLECULES COMPRISING AMINOOXY GROUPS LA JOLLA PHARMACEUTICAL COMPANY (US) 2000-12-14 WO disclosed
WO-1999064595-A9 THERAPEUTIC AND DIAGNOSTIC DOMAIN 1 β2GPI POLYPEPTIDES AND METHODS OF USING SAME JOLLA PHARMA (US) 2000-09-08 WO disclosed
WO-1999064595-A1 THERAPEUTIC AND DIAGNOSTIC DOMAIN 1 β2GPI POLYPEPTIDES AND METHODS OF USING SAME LA JOLLA PHARMACEUTICAL COMPANY (US) 1999-12-16 WO disclosed
US-4714750-A Synthesis of products from polyoxyalkylene amines and 2,6-di-t-butylphenol for use as epoxy accelerators and curing agents TEXACO INC. (US) 1987-12-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230114866-A1 VIA CYCLOADDITION BILATERALLY FUNCTIONALIZED ANTIBODIES FUT5, FUCA1, FUT6 ODC1 2187/4885ADRB2 1301/4885ADRB1 1062/4885
US-20090264366-A1 Transglutaminase Mediated Conjugation of Peptides TGM2, TGM3, TGM1 ODC1 412/4885ADRB2 4834/4885ADRB1 4813/4885
US-20100009917-A1 Modulating Enzymatic Processes by Addition of Diolcontaining Substances HSD17B14, CES2, PNLIP ODC1 361/4885ADRB2 2061/4885ADRB1 1823/4885
US-20070105770-A1 Transglutaminase mediated conjugation of peptides TGM2, TGM3, TGM1 ODC1 412/4885ADRB2 4834/4885ADRB1 4813/4885
US-20230190951-A1 CONJUGATES OF ANTIBODIES AN IMMUNE CELL ENGAGERS FCGR3B, FCGR1A, FCGR2A ODC1 4712/4885ADRB2 4829/4885ADRB1 4542/4885
US-20230364262-A1 VIA CYCLOADDITION BILATERALLY FUNCTIONALIZED ANTIBODIES FCGR1A, FCGR3B, FCGR2A ODC1 2301/4885ADRB2 767/4885ADRB1 515/4885
US-20160355859-A1 TRANSGLUTAMINASE MEDIATED CONJUGATION OF PEPTIDES TGM2, TGM3, TGM1 ODC1 412/4885ADRB2 4834/4885ADRB1 4813/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.