Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKB | O14920 | 2/20 | 0.33 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.32 |
| ▸ | RAD51 | Q06609 | 1/20 | 0.32 |
| ▸ | AR | P10275 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21092945 | 0.75 | AR (0.36) | ARPKM | |
| SCHEMBL1527275 | 0.72 | LMNA (0.40) | ARPKM | |
| SCHEMBL3391548 | 0.67 | LMNA (0.44) | MAPT | |
| SCHEMBL6962887 | 0.65 | — | — | |
| SCHEMBL12620571 | 0.65 | — | — | |
| SCHEMBL6642282 | 0.65 | — | — | |
| SCHEMBL758498 | 0.65 | RAD51 (0.46) | RAD51MAPT | |
| SCHEMBL21092943 | 0.64 | IKBKB (0.38) | IKBKBRAD51ARMAPT | |
| SCHEMBL8803221 | 0.63 | ALDH1A1 (0.45) | ARMAPT | |
| SCHEMBL8019843 | 0.63 | KDM4E (0.45) | ARMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230117324-A1 | OXAZINE MONOACYLGLYCEROL LIPASE (MAGL) INHIBITORS | HOFFMANN-LA ROCHE INC. (US) | 2023-04-20 | — | — | US | disclosed |
| US-20210107920-A1 | OXAZINE MONOACYLGLYCEROL LIPASE (MAGL) INHIBITORS | HOFFMANN-LA ROCHE INC. (US) | 2021-04-15 | — | — | US | disclosed |
| CN-111655687-A | Novel fungicidal heterocyclic compounds | PI工业有限公司 | 2020-09-11 | — | — | CN | disclosed |
| US-20200281202-A1 | NOVEL FUNGICIDAL HETEROCYCLIC COMPOUNDS | PI INDUSTRIES LTD. (IN) | 2020-09-10 | — | — | US | disclosed |
| EP-3679035-A1 | NOVEL FUNGICIDAL HETEROCYCLIC COMPOUNDS | PI Industries Ltd. (IN) | 2020-07-15 | — | — | EP | disclosed |
| WO-2019048989-A1 | NOVEL FUNGICIDAL HETEROCYCLIC COMPOUNDS | PI INDUSTRIES LTD. (IN) | 2019-03-14 | — | — | WO | disclosed |
| EP-1866287-B1 | SUBSTITUTED PYRAZOLYL OXYPHENYL DERIVATIVES USED AS HERBICIDES | BAYER IP GMBH (DE) | 2016-09-21 | — | — | EP | disclosed |
| EP-1866287-A2 | SUBSTITUTED PYRAZOLYL OXYPHENYL DERIVATIVES USED AS HERBICIDES | Bayer CropScience AG (DE) | 2007-12-19 | — | — | EP | disclosed |
| US-20060223709-A1 | Substituted pyrazolyloxyphenyl derivatives as herbicides | BAYER CROPSCIENCE GMBH (DE) | 2006-10-05 | — | — | US | disclosed |
| WO-2006103003-A2 | SUBSTITUTED PYRAZOLYL OXYPHENYL DERIVATIVES USED AS HERBICIDES | BAYER CROPSCIENCE AG (DE) | 2006-10-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210107920-A1 | OXAZINE MONOACYLGLYCEROL LIPASE (MAGL) INHIBITORS | MGLL, LPL, LIPC | IKBKB 3607/4885SMYD3 222/4885RAD51 4551/4885 |
| US-20200281202-A1 | NOVEL FUNGICIDAL HETEROCYCLIC COMPOUNDS | CYP1B1, CYP1A1, CYP51A1 | IKBKB 4071/4885SMYD3 1695/4885RAD51 4728/4885 |
| US-20230117324-A1 | OXAZINE MONOACYLGLYCEROL LIPASE (MAGL) INHIBITORS | MGLL, LPL, LIPC | IKBKB 3607/4885SMYD3 222/4885RAD51 4551/4885 |
| US-20060223709-A1 | Substituted pyrazolyloxyphenyl derivatives as herbicides | DDT, CBR3, CYP1A1 | IKBKB 4618/4885SMYD3 1926/4885RAD51 2255/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.