Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | NR3C1 | P04150 | 5/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | PGR | P06401 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | CCR1 | P32246 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5232217 | 0.85 | NR3C1 (0.40) | TAAR1NR3C1NPC1RAB9ATP53 | |
| SCHEMBL5227418 | 0.79 | PTGS1 (0.38) | NR3C1NPC1RAB9ATP53MAPT | |
| SCHEMBL5230174 | 0.78 | DRD4 (0.46) | PKMTP53MAPT | |
| SCHEMBL5227445 | 0.78 | DRD4 (0.46) | NR3C1MAPT | |
| SCHEMBL7257428 | 0.77 | ADORA2A (0.40) | NR3C1NPC1RAB9AKMT2ALMNA | |
| SCHEMBL5226500 | 0.73 | PTGS1 (0.36) | NR3C1NPC1RAB9ATP53MAPT | |
| SCHEMBL5230607 | 0.73 | DRD4 (0.46) | NR3C1TP53MAPT | |
| SCHEMBL5227774 | 0.73 | DRD3 (0.45) | TP53MAPT | |
| SCHEMBL5228024 | 0.71 | HTR2C (0.42) | NR3C1TP53PGRLMNA | |
| SCHEMBL5228140 | 0.71 | NR3C1 (0.48) | NR3C1RAB9AKMT2ATP53MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1611122-B1 | SUBSTITUTED PYRAZOLE COMPOUNDS | MERCK PATENT GMBH (DE) | 2007-06-13 | — | — | EP | disclosed |