Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP13 | P45452 | 4/20 | 0.51 |
| ▸ | MMP2 | P08253 | 4/20 | 0.51 |
| ▸ | MMP1 | P03956 | 3/20 | 0.51 |
| ▸ | MMP9 | P14780 | 2/20 | 0.51 |
| ▸ | CA1 | P00915 | 1/20 | 0.51 |
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
| ▸ | MMP8 | P22894 | 1/20 | 0.51 |
| ▸ | BMP1 | P13497 | 10/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | MMP7 | P09237 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.47 |
| ▸ | MMP3 | P08254 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5226437 | 0.83 | MMP13 (0.58) | MMP13MMP2MMP1MMP9CA1 | |
| SCHEMBL1565606 | 0.83 | MMP13 (0.58) | MMP13MMP2MMP1MMP9CA1 | |
| SCHEMBL7416701 | 0.83 | ALDH1A1 (0.58) | MMP13MMP2MMP1MMP9CA1 | |
| SCHEMBL7461414 | 0.82 | MMP13 (0.56) | MMP13MMP2MMP1MMP9CA1 | |
| SCHEMBL7417246 | 0.81 | MMP7 (0.65) | MMP13MMP2MMP1MMP9CA1 | |
| SCHEMBL8023829 | 0.79 | BMP1 (0.59) | MMP13MMP2MMP1MMP9CA1 | |
| SCHEMBL7381660 | 0.78 | MMP2 (0.75) | MMP13MMP2MMP1MMP9BMP1 | |
| SCHEMBL7381656 | 0.78 | MMP2 (0.75) | MMP13MMP2MMP1MMP9BMP1 | |
| SCHEMBL7413144 | 0.77 | BMP1 (0.60) | MMP13MMP2MMP1MMP9BMP1 | |
| SCHEMBL7419926 | 0.77 | MMP7 (0.60) | MMP13MMP2MMP1MMP9CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5863949-A | Arylsulfonylamino hydroxamic acid derivatives | PFIZER INC (US) | 1999-01-26 | — | — | US | disclosed |