Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 6/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | SMO | Q99835 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | PGR | P06401 | 2/20 | 0.32 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5222796 | 0.89 | NR3C1 (0.35) | NR3C1SMONPC1LMNARAB9A | |
| SCHEMBL5232217 | 0.78 | NR3C1 (0.40) | NR3C1TP53NPC1RAB9APGR | |
| SCHEMBL5223490 | 0.78 | SMO (0.40) | SMONPC1LMNARAB9ASMN1; SMN2 | |
| SCHEMBL5227160 | 0.78 | SMO (0.41) | SMOLMNACYP1A2CYP2C19ALDH1A1 | |
| SCHEMBL5228140 | 0.77 | NR3C1 (0.48) | NR3C1TP53SMOLMNARAB9A | |
| SCHEMBL5224829 | 0.74 | SMO (0.42) | SMOLMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL5228824 | 0.73 | ICMT (0.40) | NR3C1TP53LMNASMN1; SMN2HPGD | |
| SCHEMBL5224144 | 0.72 | HTR2C (0.38) | NR3C1SMO | |
| SCHEMBL5230496 | 0.72 | PTGS1 (0.37) | NR3C1TP53SMONPC1LMNA | |
| SCHEMBL5224226 | 0.72 | L3MBTL1 (0.36) | NR3C1TP53SMOTSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1611122-B1 | SUBSTITUTED PYRAZOLE COMPOUNDS | MERCK PATENT GMBH (DE) | 2007-06-13 | — | — | EP | disclosed |