Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMO | Q99835 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 3/20 | 0.35 |
| ▸ | DRD4 | P21917 | 3/20 | 0.35 |
| ▸ | DRD3 | P35462 | 3/20 | 0.35 |
| ▸ | AURKA | O14965 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.33 |
| ▸ | HRH2 | P25021 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5223490 | 0.89 | SMO (0.40) | SMOMAPTLMNAL3MBTL1ALDH1A1 | |
| SCHEMBL5227160 | 0.89 | SMO (0.41) | SMOMAPTLMNAL3MBTL1ALDH1A1 | |
| SCHEMBL5229662 | 0.81 | SMO (0.58) | SMOMAPTLMNAL3MBTL1ALDH1A1 | |
| SCHEMBL5224226 | 0.79 | L3MBTL1 (0.36) | SMOMAPTL3MBTL1ALDH1A1KDM4E | |
| SCHEMBL5224144 | 0.78 | HTR2C (0.38) | SMOMAPT | |
| SCHEMBL5225922 | 0.76 | L3MBTL1 (0.53) | SMOMAPTLMNAL3MBTL1ALDH1A1 | |
| SCHEMBL5222796 | 0.75 | NR3C1 (0.35) | SMOLMNAALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL5224244 | 0.74 | SMO (0.49) | SMOMAPTLMNAL3MBTL1ALDH1A1 | |
| SCHEMBL5228311 | 0.74 | NR3C1 (0.34) | SMOLMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL5228124 | 0.74 | SMO (0.43) | SMOMAPTLMNAL3MBTL1DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1611122-B1 | SUBSTITUTED PYRAZOLE COMPOUNDS | MERCK PATENT GMBH (DE) | 2007-06-13 | — | — | EP | disclosed |