Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | KCNA5 | P22460 | 2/20 | 0.41 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4781860 | 0.87 | DAGLB (0.46) | CYP1A2CYP3A4CYP2C19KDM4EMEN1 | |
| SCHEMBL4781855 | 0.87 | DAGLB (0.46) | CYP1A2CYP3A4CYP2C19KDM4EMEN1 | |
| SCHEMBL3076594 | 0.85 | LMNA (0.44) | KDM4E | |
| SCHEMBL3076592 | 0.85 | LMNA (0.44) | KDM4E | |
| SCHEMBL3533488 | 0.84 | TSHR (0.45) | KDM4E | |
| SCHEMBL3442475 | 0.83 | GPR119 (0.47) | FAAHCYP3A4KDM4EBLMALOX15 | |
| SCHEMBL5177302 | 0.81 | DPP4 (0.46) | CYP1A2CYP3A4CYP2D6KDM4EBLM | |
| SCHEMBL3540440 | 0.81 | DPP4 (0.46) | CYP1A2CYP3A4CYP2D6KDM4EBLM | |
| SCHEMBL4779673 | 0.80 | PIM2 (0.42) | KDM4E | |
| SCHEMBL4776197 | 0.80 | ROCK2 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1680418-B1 | DERIVATIVES OF N-[HETEROARYL(PIPERIDINE-2-YL)METHYL]BENZAMIDE, PREPARATION METHOD THEREOF AND APPLICATION OF SAME IN THERAPEUTICS | SANOFI AVENTIS (FR) | 2007-05-09 | — | — | EP | disclosed |