Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 5/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | ITGB3 | P05106 | 7/20 | 0.40 |
| ▸ | ITGA2B | P08514 | 7/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5238186 | 0.88 | CYP2C19 (0.43) | CYP2C9MEN1KMT2ACYP3A4TSHR | |
| SCHEMBL5239779 | 0.86 | MAPT (0.40) | CYP2C9MEN1KMT2ACYP2C19ALDH1A1 | |
| SCHEMBL5239092 | 0.85 | MEN1 (0.41) | MEN1KMT2AALDH1A1 | |
| SCHEMBL5232288 | 0.85 | MAPT (0.41) | MEN1KMT2AALDH1A1 | |
| SCHEMBL5237326 | 0.84 | CA2 (0.43) | MEN1KMT2ATSHR | |
| SCHEMBL5236546 | 0.84 | USP2 (0.46) | CYP2C9MEN1KMT2ACYP3A4TSHR | |
| SCHEMBL5233064 | 0.82 | L3MBTL1 (0.48) | MEN1KMT2AALDH1A1 | |
| SCHEMBL5234836 | 0.81 | MEN1 (0.43) | CYP2C9MEN1KMT2ACYP3A4CYP2C19 | |
| SCHEMBL5235440 | 0.81 | ALDH1A1 (0.40) | CYP2C9MEN1KMT2ACYP3A4CYP2C19 | |
| SCHEMBL5232372 | 0.81 | ALDH1A1 (0.41) | CYP2C9MEN1KMT2ACYP3A4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1701946-B1 | DERIVATIVES OF 1-PIPERAZINE- AND 1-HOMOPIPERAZINE-CARBOXYLATES, PREPARATION METHOD THEREOF AND USE OF SAME AS INHIBITORS OF THE FAAH ENZYME | SANOFI AVENTIS (FR) | 2007-12-19 | — | — | EP | claimed |