Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 10/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 8/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 8/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 7/20 | 0.46 |
| ▸ | MEN1 | O00255 | 7/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 6/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.46 |
| ▸ | HPGD | P15428 | 4/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.44 |
| ▸ | SLC6A7 | Q99884 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5238186 | 0.92 | CYP2C19 (0.43) | USP2HSD17B10ALDH1A1CYP3A4CYP1A2 | |
| SCHEMBL5232202 | 0.91 | RAB9A (0.40) | USP2HSD17B10ALDH1A1CYP3A4CYP1A2 | |
| SCHEMBL5235440 | 0.90 | ALDH1A1 (0.40) | USP2HSD17B10ALDH1A1CYP3A4CYP1A2 | |
| SCHEMBL5234836 | 0.90 | MEN1 (0.43) | USP2HSD17B10ALDH1A1CYP3A4CYP1A2 | |
| SCHEMBL5232372 | 0.89 | ALDH1A1 (0.41) | USP2HSD17B10ALDH1A1CYP3A4CYP1A2 | |
| SCHEMBL5237974 | 0.88 | RXRA (0.44) | USP2HSD17B10ALDH1A1CYP3A4CYP1A2 | |
| SCHEMBL5239779 | 0.87 | MAPT (0.40) | ALDH1A1MEN1KMT2ACYP2C9SMN1; SMN2 | |
| SCHEMBL5240792 | 0.87 | NAAA (0.42) | USP2HSD17B10ALDH1A1CYP3A4CYP1A2 | |
| SCHEMBL5232200 | 0.86 | SLC6A7 (0.42) | USP2HSD17B10ALDH1A1CYP3A4CYP1A2 | |
| SCHEMBL5235107 | 0.86 | MAPT (0.45) | ALDH1A1MEN1KMT2ASMN1; SMN2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1701946-B1 | DERIVATIVES OF 1-PIPERAZINE- AND 1-HOMOPIPERAZINE-CARBOXYLATES, PREPARATION METHOD THEREOF AND USE OF SAME AS INHIBITORS OF THE FAAH ENZYME | SANOFI AVENTIS (FR) | 2007-12-19 | — | — | EP | claimed |