SCHEMBL5654858

SCHEMBL5654858

C[Si](C)(Cl)CCCCc1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.48
MAOA P21397 1/20 0.48
SIGMAR1 Q99720 8/20 0.47
MAOB P27338 2/20 0.47
MEN1 O00255 1/20 0.44
KMT2A Q03164 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28731916 0.98 SIGMAR1 (0.50) L3MBTL1MAOASIGMAR1MAOB
SCHEMBL16207822 0.98 SIGMAR1 (0.50) L3MBTL1MAOASIGMAR1MAOB
SCHEMBL523288 0.94 L3MBTL1 (0.45) L3MBTL1MAOASIGMAR1MAOBMEN1
SCHEMBL1204279 0.88 L3MBTL1 (0.48) L3MBTL1MAOASIGMAR1MAOBMEN1
SCHEMBL22555480 0.86 SIGMAR1 (0.50) L3MBTL1MAOASIGMAR1MAOB
SCHEMBL10000437 0.86 SIGMAR1 (0.50) L3MBTL1MAOASIGMAR1MAOB
SCHEMBL523595 0.85 TDP1 (0.48) MAOAMAOB
SCHEMBL1203381 0.83 MAOA (0.52) L3MBTL1MAOASIGMAR1MAOB
SCHEMBL29000454 0.83 MAOA (0.52) L3MBTL1MAOASIGMAR1MAOBMEN1
SCHEMBL11207785 0.82 THRA (0.35) MAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025090530-A1 SUBTERRANEAN FORMATION FUNCTIONALIZATION FOR PERMEATION SELECTIVITY SAUDI ARABIAN OIL COMPANY (SA) 2025-05-01 WO claimed
US-20250137348-A1 SUBTERRANEAN FORMATION FUNCTIONALIZATION FOR PERMEATION SELECTIVITY SAUDI ARABIAN OIL COMPANY (SA) 2025-05-01 US claimed
WO-2025090530-A1 SUBTERRANEAN FORMATION FUNCTIONALIZATION FOR PERMEATION SELECTIVITY SAUDI ARABIAN OIL COMPANY (SA) 2025-05-01 WO disclosed
US-20250137348-A1 SUBTERRANEAN FORMATION FUNCTIONALIZATION FOR PERMEATION SELECTIVITY SAUDI ARABIAN OIL COMPANY (SA) 2025-05-01 US disclosed
EP-4083046-B1 METHOD FOR PREPARING HALOSILANE COMPOUNDS SHINETSU CHEMICAL CO (JP) 2025-03-26 EP disclosed
EP-3743464-B1 ORGANIC-INORGANIC AEROGEL COMPOSITES, METHODS AND USES THEREOF BRONX CREATIVE&DESIGN CENTRE PTE LTD (SG) 2024-03-06 EP disclosed
US-11731992-B2 Method for preparing halosilane compounds SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-08-22 US disclosed
US-20230250250-A1 Organic-inorganic Aerogel Composites, Methods and Uses Thereof BRONX CREATIVE & DESIGN CENTRE PTE LTD (SG) 2023-08-10 US disclosed
US-20220356195-A1 METHOD FOR PREPARING HALOSILANE COMPOUNDS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2022-11-10 US disclosed
US-20220355262-A1 SYSTEM AND METHOD FOR MANUFACTURING WATER-BASED HYDROPHOBIC AEROGELS AND AEROGEL COMPOSITES KROSSLINKER PTE LTD (SG) 2022-11-10 US disclosed
EP-4083046-A2 METHOD FOR PREPARING HALOSILANE COMPOUNDS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2022-11-02 EP disclosed
CN-114144388-A Systems and methods for manufacturing water-based hydrophobic aerogels and aerogel composites 克罗斯林克私人有限公司 2022-03-04 CN disclosed
WO-2021015676-A1 SYSTEM AND METHOD FOR MANUFACTURING WATER-BASED HYDROPHOBIC AEROGELS AND AEROGEL COMPOSITES KROSSLINKER PTE LTD (SG) 2021-01-28 WO disclosed
EP-3743464-A1 ORGANIC-INORGANIC AEROGEL COMPOSITES, METHODS AND USES THEREOF Bronx Creative&Design Centre Pte Ltd (SG) 2020-12-02 EP disclosed
WO-2019147183-A1 ORGANIC-INORGANIC AEROGEL COMPOSITES, METHODS AND USES THEREOF BRONX CREATIVE & DESIGN CENTRE PTE LTD (SG) 2019-08-01 WO disclosed
WO-2017027430-A1 PLASMA DAMAGE MANAGEMENT SBA MATERIALS, INC. (US) 2017-02-16 WO disclosed
US-8187726-B2 Nanoparticle-resin composite material, light emitting device assembly, and filling material for the light-emitting device assembly SONY CORPORATION (JP) 2012-05-29 US disclosed
US-20070036962-A1 NANO-COMPOSITE MATERIAL AND LIGHT EMITTING DEVICE SONY CORPORATION (JP) 2007-02-15 US disclosed
US-20050118742-A1 Method for reducing the adhesive properties of MEMS and anti-adhesion-coated device ROBERT BOSCH GMBH (DE) 2005-06-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220356195-A1 METHOD FOR PREPARING HALOSILANE COMPOUNDS RAD52, RPS4X, RPSA L3MBTL1 3067/4885MAOA 3589/4885SIGMAR1 346/4885
US-11731992-B2 Method for preparing halosilane compounds RAD52, RPS4X, RPSA L3MBTL1 3067/4885MAOA 3589/4885SIGMAR1 346/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.