Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 3/20 | 0.40 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | AOC3 | Q16853 | 3/20 | 0.31 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5237166 | 0.83 | AOC3 (0.41) | AOC3 | |
| SCHEMBL5237139 | 0.82 | RORC (0.37) | AOC3ENPP2 | |
| SCHEMBL5239779 | 0.81 | MAPT (0.40) | — | |
| SCHEMBL5238186 | 0.80 | CYP2C19 (0.43) | — | |
| SCHEMBL5232288 | 0.80 | MAPT (0.41) | — | |
| SCHEMBL5239092 | 0.80 | MEN1 (0.41) | — | |
| SCHEMBL5230475 | 0.80 | CYP2C9 (0.44) | — | |
| SCHEMBL5236546 | 0.79 | USP2 (0.46) | — | |
| SCHEMBL5236354 | 0.78 | CHRNB2 (0.38) | CHRNB2CHRNA4IDO1 | |
| SCHEMBL5233064 | 0.78 | L3MBTL1 (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1701946-B1 | DERIVATIVES OF 1-PIPERAZINE- AND 1-HOMOPIPERAZINE-CARBOXYLATES, PREPARATION METHOD THEREOF AND USE OF SAME AS INHIBITORS OF THE FAAH ENZYME | SANOFI AVENTIS (FR) | 2007-12-19 | — | — | EP | claimed |