Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A7 | Q99884 | 9/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.39 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.36 |
| ▸ | AOC3 | Q16853 | 4/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.36 |
| ▸ | VEGFA | P15692 | 1/20 | 0.36 |
| ▸ | FLT1 | P17948 | 1/20 | 0.36 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5236739 | 0.82 | HTR1A (0.44) | MAPT | |
| SCHEMBL5236884 | 0.82 | SLC6A7 (0.48) | SLC6A7SLC6A3PDE4BAOC3EGLN1 | |
| SCHEMBL5231072 | 0.77 | MCHR1 (0.41) | CNR2 | |
| SCHEMBL5238647 | 0.77 | USP2 (0.50) | — | |
| SCHEMBL5237168 | 0.77 | NPC1 (0.36) | SLC6A7MAPT | |
| SCHEMBL5236755 | 0.77 | MGLL (0.41) | CNR2EGLN1MAPT | |
| SCHEMBL5239724 | 0.75 | SLC6A7 (0.61) | SLC6A7SLC6A3CNR2EGLN1MAPT | |
| SCHEMBL5237020 | 0.75 | MGLL (0.47) | SLC6A7MAPT | |
| SCHEMBL5239092 | 0.74 | MEN1 (0.41) | MAPT | |
| SCHEMBL5235440 | 0.73 | ALDH1A1 (0.40) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1701946-B1 | DERIVATIVES OF 1-PIPERAZINE- AND 1-HOMOPIPERAZINE-CARBOXYLATES, PREPARATION METHOD THEREOF AND USE OF SAME AS INHIBITORS OF THE FAAH ENZYME | SANOFI AVENTIS (FR) | 2007-12-19 | — | — | EP | claimed |