Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | SLC6A7 | Q99884 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | ACACB | O00763 | 4/20 | 0.33 |
| ▸ | OGA | O60502 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5238374 | 0.85 | GPR119 (0.34) | NPC1RAB9ASLC6A7GPR119 | |
| SCHEMBL5237176 | 0.80 | NPC1 (0.35) | NPC1RAB9ASLC6A7MEN1KMT2A | |
| SCHEMBL5236873 | 0.77 | SLC6A7 (0.50) | SLC6A7MAPT | |
| SCHEMBL5237292 | 0.75 | KDM4E (0.43) | SLC6A7KDM4EGPR119ALDH1A1 | |
| SCHEMBL5238522 | 0.74 | PANK3 (0.43) | NPC1RAB9AMEN1KMT2AKDM4E | |
| SCHEMBL5238186 | 0.74 | CYP2C19 (0.43) | MEN1KMT2AMAPTALDH1A1TSHR | |
| SCHEMBL5236348 | 0.74 | CHRNB2 (0.40) | — | |
| SCHEMBL5235191 | 0.73 | ALDH1A1 (0.47) | KDM4EMAPTALDH1A1TSHRMAPK1 | |
| SCHEMBL5235184 | 0.73 | PKM (0.46) | SLC6A7KMT2AKDM4EACACBOGA | |
| SCHEMBL5237139 | 0.72 | RORC (0.37) | RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1701946-B1 | DERIVATIVES OF 1-PIPERAZINE- AND 1-HOMOPIPERAZINE-CARBOXYLATES, PREPARATION METHOD THEREOF AND USE OF SAME AS INHIBITORS OF THE FAAH ENZYME | SANOFI AVENTIS (FR) | 2007-12-19 | — | — | EP | claimed |