Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RBP4 | P02753 | 7/20 | 0.43 |
| ▸ | TTR | P02766 | 2/20 | 0.43 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 7/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | F13A1 | P00488 | 1/20 | 0.37 |
| ▸ | TGM2 | P21980 | 1/20 | 0.37 |
| ▸ | TGM1 | P22735 | 1/20 | 0.37 |
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5232924 | 0.86 | GAA (0.41) | — | |
| SCHEMBL5239767 | 0.85 | ADRA1A (0.40) | — | |
| SCHEMBL5235916 | 0.85 | AR (0.40) | AKR1C3 | |
| SCHEMBL5237871 | 0.85 | DRD2 (0.40) | AKR1C3DRD3 | |
| SCHEMBL5238575 | 0.83 | CXCR3 (0.38) | DRD3 | |
| SCHEMBL5238192 | 0.82 | CYP2C19 (0.37) | — | |
| SCHEMBL5234068 | 0.82 | DRD2 (0.45) | DRD3 | |
| SCHEMBL5238831 | 0.81 | ALDH1A1 (0.43) | — | |
| SCHEMBL5239721 | 0.80 | TSHR (0.41) | DRD3 | |
| SCHEMBL5233790 | 0.78 | CA2 (0.38) | AKR1C3DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1701946-B1 | DERIVATIVES OF 1-PIPERAZINE- AND 1-HOMOPIPERAZINE-CARBOXYLATES, PREPARATION METHOD THEREOF AND USE OF SAME AS INHIBITORS OF THE FAAH ENZYME | SANOFI AVENTIS (FR) | 2007-12-19 | — | — | EP | claimed |