Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 3/20 | 0.40 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.40 |
| ▸ | STIM1 | Q13586 | 1/20 | 0.39 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | MGLL | Q99685 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 4/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5237752 | 0.91 | RXRA (0.44) | RAB9AMGLLSMN1; SMN2MAPK1ALDH1A1 | |
| SCHEMBL5234786 | 0.90 | FFAR4 (0.44) | USP2CYP2C9SMN1; SMN2TP53CYP2C19 | |
| SCHEMBL5236555 | 0.88 | USP2 (0.41) | USP2HSD17B10CYP2C9HIF1ASMN1; SMN2 | |
| SCHEMBL5233074 | 0.87 | L3MBTL1 (0.44) | RAB9AMAPK1ALDH1A1MEN1KMT2A | |
| SCHEMBL5238652 | 0.85 | HSD17B10 (0.44) | USP2HSD17B10CYP2C9HIF1ASMN1; SMN2 | |
| SCHEMBL5237980 | 0.85 | CTSK (0.41) | — | |
| SCHEMBL5236705 | 0.84 | CD274 (0.41) | NAAAFAAHMAPK1TP53CYP2D6 | |
| SCHEMBL5232205 | 0.84 | SLC6A7 (0.41) | MGLLSMN1; SMN2ALDH1A1MAPTLMNA | |
| SCHEMBL5236998 | 0.83 | KMT2A (0.40) | RAB9AHSD17B10SMN1; SMN2MAPK1TP53 | |
| SCHEMBL5234847 | 0.82 | KMT2A (0.40) | RAB9AHSD17B10SMN1; SMN2TP53ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1701946-B1 | DERIVATIVES OF 1-PIPERAZINE- AND 1-HOMOPIPERAZINE-CARBOXYLATES, PREPARATION METHOD THEREOF AND USE OF SAME AS INHIBITORS OF THE FAAH ENZYME | SANOFI AVENTIS (FR) | 2007-12-19 | — | — | EP | claimed |