Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX3 | P56373 | 12/20 | 0.45 |
| ▸ | P2RX2 | Q9UBL9 | 12/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3116707 | 0.90 | P2RX3 (0.47) | P2RX3P2RX2MAPTHPGDALDH1A1 | |
| SCHEMBL13158515 | 0.88 | P2RX3 (0.48) | P2RX3P2RX2MAPTHPGDALDH1A1 | |
| SCHEMBL3106881 | 0.84 | ROCK2 (0.42) | MAPTHPGDALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL5244694 | 0.83 | HPGD (0.48) | MAPTHPGDALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL5247706 | 0.83 | HPGD (0.39) | MAPTHPGDALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL3112834 | 0.82 | HPGD (0.43) | MAPTHPGDALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL5245667 | 0.81 | HPGD (0.56) | MAPTHPGDALDH1A1 | |
| SCHEMBL5246905 | 0.81 | GRM5 (0.42) | MAPTHPGDALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL5244456 | 0.81 | LMNA (0.57) | MAPTALDH1A1 | |
| SCHEMBL5246544 | 0.81 | HPGD (0.38) | MAPTHPGDALDH1A1CYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1867331-A1 | TRIAZOLE DERIVATIVE AND THE USE THEREOF | Takeda Pharmaceutical Company Limited (JP) | 2007-12-19 | — | — | EP | disclosed |