Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | SMO | Q99835 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5245295 | 0.84 | LMNA (0.44) | MAPTHPGDALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL5244269 | 0.84 | CNR1 (0.49) | LMNA | |
| SCHEMBL5244456 | 0.83 | LMNA (0.57) | POLBMAPTALDH1A1L3MBTL1SMN1; SMN2 | |
| SCHEMBL5244694 | 0.83 | HPGD (0.48) | MAPTHPGDALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL3109229 | 0.83 | SMN1; SMN2 (0.48) | ALDH1A1HSD17B10SMN1; SMN2MEN1KMT2A | |
| SCHEMBL5246092 | 0.82 | EPHX2 (0.53) | L3MBTL1LMNARAB9AMEN1KMT2A | |
| SCHEMBL5249308 | 0.82 | RIPK1 (0.46) | MAPTHPGDALDH1A1LMNAMEN1 | |
| SCHEMBL5248482 | 0.82 | MEN1 (0.55) | POLBMAPTHPGDALDH1A1HSD17B10 | |
| SCHEMBL5244114 | 0.82 | CCR1 (0.43) | MAPTHPGDALDH1A1LMNAMEN1 | |
| SCHEMBL5244366 | 0.82 | CCR1 (0.45) | MAPTALDH1A1TP53LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1867331-A1 | TRIAZOLE DERIVATIVE AND THE USE THEREOF | Takeda Pharmaceutical Company Limited (JP) | 2007-12-19 | — | — | EP | disclosed |