Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MIF | P14174 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 7/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5246911 | 0.92 | NPC1 (0.45) | MIFRAB9ASMN1; SMN2NPC1HPGD | |
| SCHEMBL5244109 | 0.91 | MIF (0.47) | MIFRAB9ASMN1; SMN2NPC1HPGD | |
| SCHEMBL5246767 | 0.87 | MIF (0.47) | MIFSMN1; SMN2HPGDALDH1A1GAA | |
| SCHEMBL5244465 | 0.87 | KDM4E (0.47) | MIFRAB9ANPC1ALDH1A1KDM4E | |
| SCHEMBL5245552 | 0.87 | PDE10A (0.36) | MIFMAPK1LMNA | |
| SCHEMBL5248284 | 0.87 | NPSR1 (0.37) | MIFNPSR1 | |
| SCHEMBL5248464 | 0.86 | BRD4 (0.35) | MIFHPGDALDH1A1GAAMAPT | |
| SCHEMBL5247693 | 0.86 | LOX (0.40) | MIFRAB9ASMN1; SMN2KDM4EMAPT | |
| SCHEMBL5250068 | 0.86 | BRD4 (0.36) | MIFMAPK1 | |
| SCHEMBL5248700 | 0.86 | ROCK2 (0.41) | MIFALDH1A1MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1867331-A1 | TRIAZOLE DERIVATIVE AND THE USE THEREOF | Takeda Pharmaceutical Company Limited (JP) | 2007-12-19 | — | — | EP | disclosed |