Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.36 |
| ▸ | MIF | P14174 | 2/20 | 0.35 |
| ▸ | BRD4 | O60885 | 5/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | GLS | O94925 | 1/20 | 0.32 |
| ▸ | DDT | P30046 | 2/20 | 0.32 |
| ▸ | APP | P05067 | 1/20 | 0.32 |
| ▸ | HTR7 | P34969 | 1/20 | 0.32 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.32 |
| ▸ | BRD2 | P25440 | 1/20 | 0.32 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.32 |
| ▸ | BRDT | Q58F21 | 1/20 | 0.32 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.32 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.32 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.32 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.32 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.32 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5244591 | 0.92 | DDT (0.34) | PDE10AMIFLMNAMAPK1GLS | |
| SCHEMBL5247626 | 0.87 | MIF (0.48) | MIFLMNAMAPK1 | |
| SCHEMBL5244706 | 0.86 | ROCK2 (0.40) | PDE10AMIFBRD4DDTHTR7 | |
| SCHEMBL5244462 | 0.86 | MAPT (0.40) | MIFBRD4 | |
| SCHEMBL5250068 | 0.85 | BRD4 (0.36) | MIFBRD4MAPK1DDTPSEN1 | |
| SCHEMBL5246579 | 0.85 | WDR5 (0.38) | MIFBRD4GLSAPPBRD2 | |
| SCHEMBL5246767 | 0.85 | MIF (0.47) | MIFBRD4LMNAGLSDDT | |
| SCHEMBL5244336 | 0.84 | ROCK2 (0.42) | PDE10ABRD4GLSHTR7 | |
| SCHEMBL5246709 | 0.84 | ROCK2 (0.42) | PDE10AMIFBRD4LMNAGLS | |
| SCHEMBL5245898 | 0.84 | PPARG (0.40) | PDE10ABRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1867331-A1 | TRIAZOLE DERIVATIVE AND THE USE THEREOF | Takeda Pharmaceutical Company Limited (JP) | 2007-12-19 | — | — | EP | disclosed |