Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 2/20 | 0.39 |
| ▸ | MET | P08581 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5247254 | 0.93 | HPGD (0.44) | BRD4TP53LMNAALDH1A1HPGD | |
| SCHEMBL5247403 | 0.90 | LMNA (0.39) | LMNAALDH1A1HPGDCYP1A2CYP2C19 | |
| SCHEMBL5249047 | 0.87 | LMNA (0.38) | TP53LMNAALDH1A1HPGDCYP1A2 | |
| SCHEMBL5244933 | 0.86 | ATM (0.43) | P2RX7METALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL5247031 | 0.86 | LMNA (0.41) | P2RX7METMAOBTP53LMNA | |
| SCHEMBL5245644 | 0.86 | LMNA (0.41) | P2RX7METBRD4TP53LMNA | |
| SCHEMBL5244366 | 0.84 | CCR1 (0.45) | BRD4TP53LMNAALDH1A1MAPT | |
| SCHEMBL5244456 | 0.83 | LMNA (0.57) | LMNAALDH1A1MAPTSMN1; SMN2POLB | |
| SCHEMBL5244694 | 0.83 | HPGD (0.48) | LMNAALDH1A1HPGDCYP1A2CYP2C19 | |
| SCHEMBL5245295 | 0.83 | LMNA (0.44) | P2RX7METLMNAALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1867331-A1 | TRIAZOLE DERIVATIVE AND THE USE THEREOF | Takeda Pharmaceutical Company Limited (JP) | 2007-12-19 | — | — | EP | disclosed |