Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 5/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | BRD4 | O60885 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | NAMPT | P43490 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.41 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | HSD17B13 | Q7Z5P4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5250067 | 0.93 | P2RX7 (0.39) | HPGDLMNAPOLBGAABRD4 | |
| SCHEMBL5247403 | 0.90 | LMNA (0.39) | HPGDLMNAALDH1A1ROCK2CYP1A2 | |
| SCHEMBL5247031 | 0.89 | LMNA (0.41) | HPGDLMNAPOLBALDH1A1TP53 | |
| SCHEMBL5245644 | 0.89 | LMNA (0.41) | HPGDLMNABRD4ALDH1A1ROCK2 | |
| SCHEMBL5244694 | 0.87 | HPGD (0.48) | HPGDLMNAHTTALDH1A1MAPK1 | |
| SCHEMBL5244933 | 0.86 | ATM (0.43) | ALDH1A1ROCK2 | |
| SCHEMBL5249047 | 0.85 | LMNA (0.38) | HPGDLMNAALDH1A1ROCK2TP53 | |
| SCHEMBL5244456 | 0.85 | LMNA (0.57) | LMNAPOLBALDH1A1 | |
| SCHEMBL5245295 | 0.84 | LMNA (0.44) | HPGDLMNAGAAALDH1A1ROCK2 | |
| SCHEMBL5249308 | 0.84 | RIPK1 (0.46) | HPGDLMNAGAABRD4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1867331-A1 | TRIAZOLE DERIVATIVE AND THE USE THEREOF | Takeda Pharmaceutical Company Limited (JP) | 2007-12-19 | — | — | EP | disclosed |