Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.37 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CCR1 | P32246 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | MYC | P01106 | 3/20 | 0.34 |
| ▸ | WDR5 | P61964 | 3/20 | 0.34 |
| ▸ | MIF | P14174 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5247403 | 0.92 | LMNA (0.39) | LMNAROCK2ROCK1CYP1A2CYP2C19 | |
| SCHEMBL5244933 | 0.88 | ATM (0.43) | ROCK2ROCK1ALDH1A1CCR1MAPT | |
| SCHEMBL5250067 | 0.87 | P2RX7 (0.39) | LMNACYP1A2CYP2C19HPGDALDH1A1 | |
| SCHEMBL5245295 | 0.86 | LMNA (0.44) | LMNAROCK2ROCK1CYP1A2CYP2C19 | |
| SCHEMBL5245644 | 0.85 | LMNA (0.41) | LMNAROCK2ROCK1CYP1A2CYP2C19 | |
| SCHEMBL5247254 | 0.85 | HPGD (0.44) | LMNAROCK2CYP1A2CYP2C19HPGD | |
| SCHEMBL5244456 | 0.85 | LMNA (0.57) | LMNAALDH1A1MAPTMIF | |
| SCHEMBL5249308 | 0.84 | RIPK1 (0.46) | LMNAROCK2ROCK1CYP1A2CYP2C19 | |
| SCHEMBL5244114 | 0.84 | CCR1 (0.43) | LMNAHPGDALDH1A1CCR1MAPT | |
| SCHEMBL5247031 | 0.84 | LMNA (0.41) | LMNACYP1A2CYP2C19HPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1867331-A1 | TRIAZOLE DERIVATIVE AND THE USE THEREOF | Takeda Pharmaceutical Company Limited (JP) | 2007-12-19 | — | — | EP | disclosed |