Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | JAK2 | O60674 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA4 | P22748 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.31 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9584860 | 0.84 | KDM4E (0.46) | KDM4ELMNAMAPTJAK2GAA | |
| SCHEMBL9798227 | 0.82 | KDM4E (0.36) | KDM4ELMNAMAPTJAK2GAA | |
| SCHEMBL2769030 | 0.78 | DRD1 (0.42) | KDM4ELMNAMAPTJAK2GAA | |
| SCHEMBL9217603 | 0.78 | KDM4E (0.33) | KDM4ELMNAMAPTJAK2GAA | |
| SCHEMBL790910 | 0.78 | CYP1A2 (0.37) | KDM4ELMNAMAPTJAK2GAA | |
| SCHEMBL2536766 | 0.78 | KDM4E (0.33) | KDM4ELMNAMAPTJAK2GAA | |
| SCHEMBL7474927 | 0.78 | KDM4E (0.43) | KDM4ELMNAMAPTJAK2GAA | |
| SCHEMBL93705 | 0.78 | ALDH1A1 (0.56) | KDM4EMAPTGAAALDH1A1HPGD | |
| SCHEMBL27641064 | 0.76 | ALDH1A1 (0.54) | KDM4EMAPTGAAALDH1A1HPGD | |
| SCHEMBL910763 | 0.75 | HPGD (0.53) | KDM4ELMNAMAPTALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2797992-B1 | DIGLYCERIN DERIVATE-MODIFIED SILICONE, EMULSIFIER FOR WATER-IN-OIL EMULSION USING THE SAME, EXTERNAL USE PREPARATION, AND COSMETIC COMPOSITION | DOW CORNING TORAY CO LTD (JP) | 2019-04-17 | — | — | EP | disclosed |
| US-10085928-B2 | Diglycerin derivate-modified silicone, emulsifier for water-in-oil emulsion using the same, external use preparaton, and cosmetic composition | DOW CORNING TORAY CO., LTD. (JP) | 2018-10-02 | — | — | US | disclosed |
| US-9585832-B2 | Organopolysiloxane elastomer modified with mono-/diglycerin derivative, and use therefor | DOW CORNING TORAY CO., LTD. (JP) | 2017-03-07 | — | — | US | disclosed |
| US-9480630-B2 | Co-modified organopolysiloxane, emulsifier for water-in-oil emulsion, external use preparation, and cosmetic composition using the same | DOW CORNING TORAY CO., LTD. (JP) | 2016-11-01 | — | — | US | disclosed |
| EP-2598113-B1 | COSMETIC FOR HAIR CONTAINING CO-MODIFIED ORGANOPOLYSILOXANE | DOW CORNING TORAY CO LTD (JP) | 2016-04-20 | — | — | EP | disclosed |
| US-9301913-B2 | Organo polysiloxane elastomer and use therefor | DOW CORNING TORAY CO., LTD. (JP) | 2016-04-05 | — | — | US | disclosed |
| US-20150011656-A1 | Co-Modified Organopolysiloxane, Emulsifier For Water-In-Oil Emulsion, External Use Preparation, And Cosmetic Composition Using The Same | DOW TORAY CO., LTD. (JP) | 2015-01-08 | — | — | US | disclosed |
| US-20150004107-A1 | Diglycerin Derivate-Modified Silicone, Emulsifier For Water-In-Oil Emulsion Using The Same, External Use Preparation, And Cosmetic Composition | DOW TORAY CO., LTD. (JP) | 2015-01-01 | — | — | US | disclosed |
| EP-2797992-A1 | DIGLYCERIN DERIVATE-MODIFIED SILICONE, EMULSIFIER FOR WATER-IN-OIL EMULSION USING THE SAME, EXTERNAL USE PREPARATION, AND COSMETIC COMPOSITION | Dow Corning Toray Co., Ltd. (JP) | 2014-11-05 | — | — | EP | disclosed |
| EP-2797989-A1 | CO-MODIFIED ORGANOPOLYSILOXANE, EMULSIFIER FOR WATER-IN-OIL EMULSION, EXTERNAL USE PREPARATION, AND COSMETIC COMPOSITION USING THE SAME | Dow Corning Toray Co., Ltd. (JP) | 2014-11-05 | — | — | EP | disclosed |
| WO-2013100169-A1 | CO-MODIFIED ORGANOPOLYSILOXANE, EMULSIFIER FOR WATER-IN-OIL EMULSION, EXTERNAL USE PREPARATION, AND COSMETIC COMPOSITION USING THE SAME | DOW CORNING TORAY CO., LTD. (JP) | 2013-07-04 | — | — | WO | disclosed |
| US-20130142748-A1 | Cosmetic For Hair Containing Co-Modified Organopolysiloxane | DOW CORNING TORAY CO., LTD. (JP) | 2013-06-06 | — | — | US | disclosed |
| EP-2598113-A1 | COSMETIC FOR HAIR CONTAINING CO-MODIFIED ORGANOPOLYSILOXANE | Dow Corning Toray Co., Ltd. (JP) | 2013-06-05 | — | — | EP | disclosed |
| EP-2563863-A1 | COSMETIC RAW MATERIAL | Dow Corning Corporation (US) | 2013-03-06 | — | — | EP | disclosed |
| US-20130046028-A1 | Cosmetic Raw Material | DOW CORNING TORAY CO., LTD. (JP) | 2013-02-21 | — | — | US | disclosed |
| US-20120328539-A1 | Thickener Or Gellant For Oil Materials, Gel Composition Comprising Same, And Method Of Producing Cosmetic Material Or Topical Agent | DOW TORAY CO., LTD. (JP) | 2012-12-27 | — | — | US | disclosed |
| EP-2516511-A2 | THICKENER OR GELLANT FOR OIL MATERIALS, GEL COMPOSITION COMPRISING SAME, AND METHOD OF PRODUCING COSMETIC MATERIAL OR TOPICAL AGENT | Dow Corning Toray Co., Ltd. (JP) | 2012-10-31 | — | — | EP | disclosed |
| WO-2012015070-A1 | COSMETIC FOR HAIR CONTAINING CO-MODIFIED ORGANOPOLYSILOXANE | DOW CORNING TORAY CO., LTD. (JP) | 2012-02-02 | — | — | WO | disclosed |
| WO-2011137212-A1 | COSMETIC RAW MATERIAL | DOW CORNING CORPORATION (US) | 2011-11-03 | — | — | WO | disclosed |
| WO-2011078395-A2 | THICKENER OR GELLANT FOR OIL MATERIALS, GEL COMPOSITION COMPRISING SAME, AND METHOD OF PRODUCING COSMETIC MATERIAL OR TOPICAL AGENT | DOW CORNING TORAY CO., LTD. (JP) | 2011-06-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120328539-A1 | Thickener Or Gellant For Oil Materials, Gel Composition Comprising Same, And Method Of Producing Cosmetic Material Or Topical Agent | H1-10, F12, RPS12 | KDM4E 2750/4885LMNA 1609/4885MAPT 4057/4885 |
| US-20150011656-A1 | Co-Modified Organopolysiloxane, Emulsifier For Water-In-Oil Emulsion, External Use Preparation, And Cosmetic Composition Using The Same | H1-10, F12, H1-0 | KDM4E 4066/4885LMNA 3366/4885MAPT 4446/4885 |
| US-20150004107-A1 | Diglycerin Derivate-Modified Silicone, Emulsifier For Water-In-Oil Emulsion Using The Same, External Use Preparation, And Cosmetic Composition | DGAT1, DGKI, DGAT2 | KDM4E 2756/4885LMNA 1141/4885MAPT 4654/4885 |
| US-20130046028-A1 | Cosmetic Raw Material | LIPA, CUTA, F12 | KDM4E 2089/4885LMNA 256/4885MAPT 4545/4885 |
| US-10085928-B2 | Diglycerin derivate-modified silicone, emulsifier for water-in-oil emulsion using the same, external use preparaton, and cosmetic composition | PLIN3, PLIN5, DEGS1 | KDM4E 2700/4885LMNA 79/4885MAPT 4764/4885 |
| US-20130142748-A1 | Cosmetic For Hair Containing Co-Modified Organopolysiloxane | FSCN1, DSG1, DSTN | KDM4E 2366/4885LMNA 2492/4885MAPT 3997/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.