Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 2/20 | 0.89 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.59 |
| ▸ | CDK1 | P06493 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | TYR | P14679 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | TAS2R38 | P59533 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5427766 | 0.94 | KIF11 (1.00) | KIF11EPHX2CDK1ALDH1A1TP53 | |
| Acrylamide SCHEMBL28438109 | 0.87 | KIF11 (0.69) | KIF11EPHX2CDK1ALDH1A1PTGS1 | |
| SCHEMBL9187022 | 0.83 | KIF11 (0.65) | KIF11EPHX2CDK1ALDH1A1TAS2R38 | |
| SCHEMBL9453957 | 0.83 | CDK1 (0.68) | KIF11EPHX2CDK1ALDH1A1LMNA | |
| SCHEMBL11057676 | 0.82 | KIF11 (0.63) | KIF11EPHX2CDK1ALDH1A1PTGS1 | |
| SCHEMBL725810 | 0.82 | ALDH1A1 (0.75) | KIF11ALDH1A1TP53TYRTSHR | |
| SCHEMBL457226 | 0.80 | IDO1 (0.65) | KIF11EPHX2CDK1ALDH1A1LMNA | |
| SCHEMBL167549 | 0.79 | KIF11 (0.89) | KIF11EPHX2ALDH1A1PTGS1TGM2 | |
| SCHEMBL20560147 | 0.79 | KIF11 (0.59) | KIF11EPHX2CDK1ALDH1A1PTGS1 | |
| SCHEMBL4348957 | 0.79 | KIF11 (0.59) | KIF11EPHX2ALDH1A1TP53TYR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 120 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117820332-A | Benzothiophene-thiourea compound and preparation method and application thereof | 烟台大学 | 2024-04-05 | — | — | CN | claimed |
| CN-112888674-B | Polycyclic compounds as soluble epoxide hydrolase inhibitors | 巴塞罗那大学 | 2023-06-30 | — | — | CN | claimed |
| US-20210283023-A1 | Dual-Curing Dental Compositions with High Stability | JAMES R. GLIDEWELL DENTAL CERAMICS, INC. | 2021-09-16 | — | — | US | claimed |
| US-11020324-B2 | Dual-curing dental compositions with high stability | JAMES R. GLIDEWELL DENTAL CERAMICS, INC. (US) | 2021-06-01 | — | — | US | claimed |
| US-20200268615-A1 | Dual-Curing Dental Compositions with High Stability | JAMES R. GLIDEWELL DENTAL CERAMICS, INC. | 2020-08-27 | — | — | US | claimed |
| CN-105536747-B | A kind of intelligent response liquid chromatography stuffing and preparation method thereof | 重庆大学 | 2018-02-02 | — | — | CN | claimed |
| CN-101687816-A | Triaminopyrimidine derivatives as the CDC25 inhibitors of phosphatases | IPSEN PHARMA SAS | 2010-03-31 | — | — | CN | claimed |
| US-20250011315-A1 | ARYL HYDROCARBON RECEPTOR (AHR) AGONISTS AND USES THEREOF | PRISM MEDICINES, INC. | 2025-01-09 | — | — | US | disclosed |
| US-20240390333-A1 | NEUROPROTECTIVE COMPOSITIONS AND METHODS OF USING THE SAME | THE BOARD OF SUPERVISORS OF LOUISIANA STATE UNIV AND AGRICULTURAL AND MECHANICAL COLLEGE (US) | 2024-11-28 | — | — | US | disclosed |
| CN-107629022-B | Antibacterial synergist and preparation method and application thereof | 上海医药工业研究院 | 2024-11-12 | — | — | CN | disclosed |
| CN-118619952-A | Aloperine derivative, preparation method, pharmaceutical composition and application thereof | 中国医学科学院药物研究所 | 2024-09-10 | — | — | CN | disclosed |
| US-12030876-B2 | Aryl hydrocarbon receptor (AHR) agonists and uses thereof | Ikena Oncology, Inc. (US) | 2024-07-09 | — | — | US | disclosed |
| US-12030876-B2 | Aryl hydrocarbon receptor (AHR) agonists and uses thereof | Ikena Oncology, Inc. (US) | 2024-07-09 | — | — | US | disclosed |
| US-20070010671-A1 | Novel quinazoline derivatives and methods of treatment related to the use thereof | ARENA PHARMACEUTICALS, INC. | 2007-01-11 | — | — | US | disclosed |
| CN-1826322-A | Diaryl and arylheteroaryl urea derivatives as modulators of the 5-HT 2A serotonin receptor for the prevention and treatment of related disorders | ARENA PHARM INC (US) | 2006-08-30 | — | — | CN | disclosed |
| US-20050256175-A1 | Novel glucagon antagonists/inverse agonists | LAU JESPER | 2005-11-17 | — | — | US | disclosed |
| US-6881746-B2 | Glucagon antagonists/inverse agonists | NOVO NORDICK A/S (DK) | 2005-04-19 | — | — | US | disclosed |
| EP-1519723-A1 | NOVEL GLUCAGON ANTAGONISTS/INVERSE AGONISTS | NOVO NORDISK A/S (DK) | 2005-04-06 | — | — | EP | disclosed |
| US-20040014789-A1 | Novel glucagon antagonists/inverse agonists | NOVO NORDISK A/S (DK) | 2004-01-22 | — | — | US | disclosed |
| WO-2004002480-A1 | NOVEL GLUCAGON ANTAGONISTS/INVERSE AGONISTS | NOVO NORDISK A/S (DK) | 2004-01-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040014789-A1 | Novel glucagon antagonists/inverse agonists | GLP1R, GCGR, GIPR | KIF11 3979/4885EPHX2 3617/4885CDK1 4062/4885 |
| US-20250011315-A1 | ARYL HYDROCARBON RECEPTOR (AHR) AGONISTS AND USES THEREOF | AHR, ARNT, HCAR1 | KIF11 4800/4885EPHX2 341/4885CDK1 4730/4885 |
| US-12030876-B2 | Aryl hydrocarbon receptor (AHR) agonists and uses thereof | AHR, ARNT, HCAR1 | KIF11 4800/4885EPHX2 341/4885CDK1 4730/4885 |
| US-20070010671-A1 | Novel quinazoline derivatives and methods of treatment related to the use thereof | MCHR1, GPR119, MCHR2 | KIF11 1709/4885EPHX2 3017/4885CDK1 1006/4885 |
| US-20050256175-A1 | Novel glucagon antagonists/inverse agonists | GLP1R, GCGR, GIPR | KIF11 3979/4885EPHX2 3617/4885CDK1 4062/4885 |
| US-20240390333-A1 | NEUROPROTECTIVE COMPOSITIONS AND METHODS OF USING THE SAME | GAP43, NLN, SMN1; SMN2 | KIF11 1011/4885EPHX2 889/4885CDK1 3674/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.