Pivalate

Pivalate

SCHEMBL526147

CC(C)(C)C(=O)O.CC(C)(C)C(=O)O.CCCCC(C)(O)O

nearest known ligand 0.42

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.39
ALDH1A1 P00352 3/20 0.39
AKR1B1 P15121 1/20 0.37
CA2 P00918 1/20 0.37
MAPK1 P28482 1/20 0.37
PPARG P37231 5/20 0.36
PPARD Q03181 5/20 0.36
PPARA Q07869 5/20 0.36
HDAC11 Q96DB2 4/20 0.36
GPR84 Q9NQS5 3/20 0.36
TLR2 O60603 2/20 0.36
TDP1 Q9NUW8 2/20 0.36
FABP4 P15090 2/20 0.36
PTPN1 P18031 2/20 0.36
SLC22A6 Q4U2R8 1/20 0.36
SLC22A8 Q8TCC7 1/20 0.36
MEN1 O00255 1/20 0.36
ESR1 P03372 1/20 0.36
ALOX15 P16050 1/20 0.36
PDE4A P27815 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Pivalate SCHEMBL28798435 0.88 LMNA (0.37) TSHRALDH1A1HSD17B10
SCHEMBL123130 0.84
Adipic Acid SCHEMBL3690204 0.82 AKR1B1 (0.62) TSHRALDH1A1AKR1B1PPARGPPARD
SCHEMBL28206327 0.82 CA2 (0.43) CA2MAPK1PPARDGPR84FFAR1
Pivalate SCHEMBL10837336 0.82 AKR1B1 (0.52) TSHRALDH1A1AKR1B1PPARGPPARD
Sebacic Acid SCHEMBL28729977 0.80 GPR84 (0.64) TSHRALDH1A1AKR1B1PPARGPPARD
SCHEMBL605019 0.80 TSHR (0.43) TSHRALDH1A1AKR1B1CA2MAPK1
SCHEMBL2103333 0.80 TSHR (0.43) TSHRALDH1A1AKR1B1CA2MAPK1
SCHEMBL381209 0.80 TSHR (0.43) TSHRALDH1A1AKR1B1CA2MAPK1
Octane SCHEMBL29057202 0.79 GPR84 (0.55) TSHRALDH1A1AKR1B1PPARGPPARD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 156 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12569428-B2 Oil-in-water cleansing cosmetic composition DOW TORAY CO., LTD. (JP) 2026-03-10 US disclosed
EP-3368592-B1 COSMETIC COMPOSITION, COSMETIC, AND EXTERNAL PREPARATION FOR SKIN DOW TORAY CO LTD (JP) 2025-12-03 EP disclosed
EP-3954357-B1 OIL-IN-WATER-TYPE CLEANSING COSMETIC DOW TORAY CO LTD (JP) 2025-10-29 EP disclosed
US-12453694-B2 Cosmetic composition DOW TORAY CO., LTD. (JP) 2025-10-28 US disclosed
EP-3778780-B1 OIL AGENT-CONTAINING SILICONE ELASTOMER PARTICLE AND USE THEREOF IN COSMETIC COMPOSITION, ETC DOW TORAY CO LTD (JP) 2025-07-16 EP disclosed
WO-2025052869-A1 EXTERNAL-USE COMPOSITION AND METHOD FOR ENHANCING FRAGRANCE OF SAME ロート製薬株式会社 2025-03-13 WO disclosed
US-12133910-B2 Oil agent-containing silicone elastomer particle and use thereof in cosmetic composition, etc DOW TORAY CO., LTD. (JP) 2024-11-05 US disclosed
WO-2024214823-A1 LIQUID COMPOSITION, DISCHARGE PRODUCT, AND AEROSOL PRODUCT 株式会社ダイゾー 2024-10-17 WO disclosed
US-20240099955-A1 SKINCARE COMPOSITIONS AND METHODS OF USE THEREOF HTL BIOTECHNOLOGY INNOVATION INC. 2024-03-28 US disclosed
EP-3132789-B1 COSMETIC DOW TORAY CO LTD (JP) 2024-01-17 EP disclosed
WO-2012015070-A1 COSMETIC FOR HAIR CONTAINING CO-MODIFIED ORGANOPOLYSILOXANE DOW CORNING TORAY CO., LTD. (JP) 2012-02-02 WO disclosed
WO-2012015069-A1 COSMETIC FOR HAIR CONTAINING SUGAR ALCOHOL-MODIFIED SILICONE DOW CORNING TORAY CO., LTD. (JP) 2012-02-02 WO disclosed
WO-2011136389-A2 COSMETIC AND TOPICAL SKIN PREPARATION COMPRISING HIGHER ALCOHOL-MODIFIED SILICONE DOW CORNING TORAY CO., LTD. (JP) 2011-11-03 WO disclosed
WO-2011136393-A1 ORGANOPOLYSILOXANE AND USE THEREOF AS SURFACTANT, POWDER TREATMENT AGENT, THICKENING AGENT OF OIL -BASED RAW MATERIAL OR GELLING AGENT. GEL AND EMULSION COMPOSITIONS, AS WELL AS, PREPARATIONS FOR EXTERNAL USE AND COSMETICS COMPRISING THE SAME DOW CORNING TORAY CO., LTD. (JP) 2011-11-03 WO disclosed
WO-2011136394-A1 POWDER TREATMENT AGENT COMPRISING SUGAR ALCOHOL -MODIFIED ORGANOPOLYSILOXANE DOW CORNING TORAY CO., LTD. (JP) 2011-11-03 WO disclosed
WO-2011136397-A1 NOVEL ORGANOPOLYSILOXANE, SURFACTANT, EMULSION COMPOSITION, POWDER TREATMENT AGENT, THICKENING AGENT OF OIL-BASED RAW MATERIAL, GELLING AGENT, GEL COMPOSITION, AND COSMETIC RAW MATERIAL COMPRISING NOVEL ORGANOPOLYSILOXANE, AS WELL AS, PREPARATION FOR EXTERNAL USE AND COSMETIC COMPRISING THE SAME DOW CORNING TORAY CO., LTD. (JP) 2011-11-03 WO disclosed
WO-2011081218-A1 PHENYL-CONTAINING ORGANOPOLYSILOXANE COMPOSITION, RAW COSMETIC MATERIAL, AND GLOSSY COSMETIC MATERIAL DOW CORNING TORAY CO., LTD. (JP) 2011-07-07 WO disclosed
WO-2011078407-A1 COPOLYMER HAVING CARBOSILOXANE DENDRIMER STRUCTURE, AND COMPOSITION AND COSMETIC CONTAINING THE SAME DOW CORNING TORAY CO., LTD. (JP) 2011-06-30 WO disclosed
WO-2011078395-A2 THICKENER OR GELLANT FOR OIL MATERIALS, GEL COMPOSITION COMPRISING SAME, AND METHOD OF PRODUCING COSMETIC MATERIAL OR TOPICAL AGENT DOW CORNING TORAY CO., LTD. (JP) 2011-06-30 WO disclosed
WO-2011068251-A1 PRODUCTION METHOD OF DEODORIZED POLYOXYALKYLENE-MODIFIED POLYSILOXANE COMPOSITION DOW CORNING TORAY CO., LTD. (JP) 2011-06-09 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12569428-B2 Oil-in-water cleansing cosmetic composition SGMS2, SGMS1, CUTA TSHR 1036/4885ALDH1A1 1607/4885AKR1B1 4299/4885
US-12453694-B2 Cosmetic composition CUTA, SLC30A7, SLC39A7 TSHR 1626/4885ALDH1A1 2513/4885AKR1B1 4255/4885
US-12133910-B2 Oil agent-containing silicone elastomer particle and use thereof in cosmetic composition, etc CUTA, SGMS2, NOTUM TSHR 3050/4885ALDH1A1 2517/4885AKR1B1 4158/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.