Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.50 |
| ▸ | CA1 | P00915 | 2/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | MMP1 | P03956 | 1/20 | 0.47 |
| ▸ | MMP2 | P08253 | 1/20 | 0.47 |
| ▸ | MMP9 | P14780 | 1/20 | 0.47 |
| ▸ | MMP8 | P22894 | 1/20 | 0.47 |
| ▸ | MMP13 | P45452 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA3 | P07451 | 1/20 | 0.46 |
| ▸ | CA6 | P23280 | 1/20 | 0.46 |
| ▸ | CA5A | P35218 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.46 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.45 |
| ▸ | VDR | P11473 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Toluene SCHEMBL28278505 | 0.92 | VDR (0.47) | GAACA1CA2MMP1MMP2 | |
| SCHEMBL6490 | 0.86 | GAA (0.59) | GAACA1CA2MMP1MMP2 | |
| Water SCHEMBL3352692 | 0.84 | GAA (0.56) | GAACA1CA2MMP1MMP2 | |
| SCHEMBL30862469 | 0.84 | GAA (0.56) | GAACA1CA2MMP1MMP2 | |
| SCHEMBL528132 | 0.83 | ALDH1A1 (0.50) | GAACA1CA2MMP1MMP2 | |
| SCHEMBL527713 | 0.83 | ALDH1A1 (0.50) | GAACA1CA2MMP1MMP2 | |
| SCHEMBL21072819 | 0.81 | ACHE (0.54) | GAACA1CA2MMP1MMP2 | |
| SCHEMBL2966008 | 0.80 | GAA (0.52) | GAACA1CA2MMP1MMP2 | |
| SCHEMBL344977 | 0.80 | GAA (0.52) | GAACA1CA2MMP1MMP2 | |
| SCHEMBL66115 | 0.80 | GAA (0.52) | GAACA1CA2MMP1MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 74 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3071191-B1 | SLOW-RELEASE SOLID ORAL COMPOSITIONS | GNOSIS SPA (IT) | 2022-01-05 | — | — | EP | claimed |
| EP-3071191-A1 | SLOW-RELEASE SOLID ORAL COMPOSITIONS | Gnosis S.p.A. (IT) | 2016-09-28 | — | — | EP | claimed |
| WO-2015071806-A1 | SLOW-RELEASE SOLID ORAL COMPOSITIONS | GNOSIS SPA (IT) | 2015-05-21 | — | — | WO | claimed |
| EP-1754468-B1 | Use of quaternary polysiloxanes in wash and personal care products | CLARIANT PRODUKTE DEUTSCHLAND (DE) | 2009-04-08 | — | — | EP | claimed |
| US-7511165-B2 | Amino-functional silicone waxes | CLARIANT FINANCE (BVI) LIMITED (VG) | 2009-03-31 | — | — | US | claimed |
| US-20080242826-A1 | Multiple Quartenary Polysiloxanes | CLARIANT FINANCE (BVI) LIMITED (VG) | 2008-10-02 | — | — | US | claimed |
| US-20070122372-A1 | Amino-functional silicone waxes | CLARIANT FINANCE (BVI) LIMITED (VG) | 2007-05-31 | — | — | US | claimed |
| US-20070041930-A1 | Use of quaternary polysiloxanes in cleaning and care compositions | CLARIANT PRODUKTE (DEUTSCHLAND) GMBH) | 2007-02-22 | — | — | US | claimed |
| EP-1678239-A1 | AMINO-FUNCTIONAL SILICONE WAXES | Clariant International Ltd. (CH) | 2006-07-12 | — | — | EP | claimed |
| EP-1678238-A1 | MULTIPLE QUATERNARY POLYSILOXANES | Clariant International Ltd. (CH) | 2006-07-12 | — | — | EP | claimed |
| WO-2005035631-A1 | AMINO-FUNCTIONAL SILICONE WAXES | CLARIANT INTERNATIONAL LTD (CH) | 2005-04-21 | — | — | WO | claimed |
| WO-2005035628-A1 | MULTIPLE QUATERNARY POLYSILOXANES | CLARIANT INTERNATIONAL LTD (CH) | 2005-04-21 | — | — | WO | claimed |
| US-20240145031-A1 | Methods and devices for drug repositioning and drug repurposing as nuclear receptor modulators | Precision Medicine Lab (NL) | 2024-05-02 | — | — | US | disclosed |
| WO-2022268969-A1 | ß-LACTAM ANTIBIOTIC WITH SIGNIFICANT ACTIVITY AGAINST CANCER E.G. COLON MALIGNANCIES | UNIVERSITÄT REGENSBURG (DE) | 2022-12-29 | — | — | WO | disclosed |
| EP-4108244-A1 | SS-LACTAM ANTIBIOTIC WITH SIGNIFICANT ACTIVITY AGAINST CANCER E.G. COLON MALIGNANCIES | Universität Regensburg (DE) | 2022-12-28 | — | — | EP | disclosed |
| EP-3071191-B1 | SLOW-RELEASE SOLID ORAL COMPOSITIONS | GNOSIS SPA (IT) | 2022-01-05 | — | — | EP | disclosed |
| US-4639468-A | Derivatives of glycinamide, their preparation and their use | CONTINENTAL PHARMA INC. (BE) | 1987-01-27 | — | — | US | disclosed |
| EP-0000092-B1 | METHOD OF PREPARING ASCORBIC ACID AND INTERMEDIATES SPECIALLY ADAPTED FOR USE THEREIN | PFIZER INC. (US) | 1981-04-29 | — | — | EP | disclosed |
| US-4115547-A | ULTRAVIOLET LIGHT ABSORBERS WITH TWO OR MORE ESTER, THIOESTER AND/OR AMIDE GROUPS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1978-09-19 | — | — | US | disclosed |
| US-4002733-A | WATER RESISTANCE | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1977-01-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070041930-A1 | Use of quaternary polysiloxanes in cleaning and care compositions | KRT18, POLR1C, CUTA | GAA 3533/4885CA1 1720/4885CA2 2154/4885 |
| US-20070122372-A1 | Amino-functional silicone waxes | PNISR, SRSF6, CUTA | GAA 4453/4885CA1 4690/4885CA2 4864/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.