Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | SYK | P43405 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | NCF1 | P14598 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.46 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.46 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | MPO | P05164 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13876457 | 1.00 | LOXL2 (0.48) | LOXL2SMN1; SMN2SYKGAAALOX15 | |
| SCHEMBL9601934 | 0.87 | SYK (0.54) | SMN1; SMN2SYKGAAALOX15MAPK1 | |
| SCHEMBL19938062 | 0.85 | TLR8 (0.47) | LOXL2NCF1HTR1AADRA1DADRA1A | |
| SCHEMBL16836384 | 0.84 | TLR8 (0.49) | LOXL2GAANCF1TLR8CYP1A2 | |
| SCHEMBL28875442 | 0.83 | SYK (0.37) | LOXL2SMN1; SMN2SYKGAAALOX15 | |
| SCHEMBL7561580 | 0.82 | TLR8 (0.50) | LOXL2SMN1; SMN2HTTNCF1TLR8 | |
| SCHEMBL828159 | 0.82 | GAK (0.55) | LOXL2SMN1; SMN2SYKALOX15HTT | |
| SCHEMBL7590766 | 0.81 | TLR8 (0.51) | SMN1; SMN2HTTNCF1HTR1AADRA1D | |
| SCHEMBL12410468 | 0.81 | LOXL2 (0.63) | LOXL2SMN1; SMN2NCF1HTR1AADRA1D | |
| SCHEMBL28010963 | 0.81 | LOXL2 (0.48) | LOXL2NCF1HTR1AADRA1DADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108576400-A | A kind of nanometer vitamin C for animal feed adds coating technique | 南京佳果生物科技有限公司 | 2018-09-28 | — | — | CN | claimed |
| CN-107604469-A | A kind of nano combined foaming rope and preparation method | 界首市宏利塑料有限公司 | 2018-01-19 | — | — | CN | claimed |
| US-11780849-B2 | Imino sulfanone inhibitors of ENPP1 | VOLASTRA THERAPEUTICS, INC. (US) | 2023-10-10 | — | — | US | disclosed |
| US-20230183226-A1 | AKT3 MODULATORS | Georgiamune Inc. | 2023-06-15 | — | — | US | disclosed |
| CN-109134362-B | Method for introducing nitrogen heterocycle through decarboxylation of carboxylate with light-induced nonmetal catalytic activity | 中国科学技术大学 | 2020-08-25 | — | — | CN | disclosed |
| WO-2020063399-A1 | METHOD FOR LIGHT-INDUCED DECARBOXYLATION COUPLING OF ACTIVE CARBOXYLIC ACID ESTER UNDER NON-METAL CATALYSIS | 中国科学技术大学 | 2020-04-02 | — | — | WO | disclosed |
| WO-2020063399-A1 | METHOD FOR LIGHT-INDUCED DECARBOXYLATION COUPLING OF ACTIVE CARBOXYLIC ACID ESTER UNDER NON-METAL CATALYSIS | 中国科学技术大学 | 2020-04-02 | — | — | WO | disclosed |
| CN-103360791-B | Colorant dispersion | 住友化学株式会社 | 2019-06-07 | — | — | CN | disclosed |
| CN-109134362-A | A kind of method that the nonmetal catalyzed active carboxylic acid's ester decarboxylation of photoinduction introduces azacyclo- | 中国科学技术大学 | 2019-01-04 | — | — | CN | disclosed |
| US-10023538-B2 | Compounds, compositions and associated methods comprising 3-aryl quinolines | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS (US) | 2018-07-17 | — | — | US | disclosed |
| CN-104971918-B | Cleaning industrial equipment part is to remove the method for metal halide | 瓦克化学股份公司 | 2018-03-13 | — | — | CN | disclosed |
| US-20100010224-A1 | PROCESS FOR PRODUCTION OF HETEROARYL-TYPE BORON COMPOUNDS WITH IRIDIUM CATALYST | MITSUBISHI RAYON CO., LTD. (JP) | 2010-01-14 | — | — | US | disclosed |
| US-7612218-B2 | Process for production of heteroaryl-type boron compounds with iridium catalyst | MITSUBISHI RAYON CO., LTD. (JP) | 2009-11-03 | — | — | US | disclosed |
| US-20090099220-A1 | ANTIMALARIAL COMPOUNDS WITH FLEXIBLE SIDE-CHAINS | MEDICINES FOR MALARIA VENTURE | 2009-04-16 | — | — | US | disclosed |
| US-20050148775-A1 | Process for production of heteroaryl-type boron compounds with iridium catalyst | MITSUBISHI RAYON CO., LTD. (JP) | 2005-07-07 | — | — | US | disclosed |
| EP-1481978-A1 | PROCESS FOR PRODUCTION OF HETEROARYL-TYPE BORON COMPOUNDS WITH IRIDIUM CATALYST | Mitsubishi Rayon Co., Ltd. (JP) | 2004-12-01 | — | — | EP | disclosed |
| WO-2003053349-A2 | INHIBITORS OF HEPATITIS C VIRUS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2003-07-03 | — | — | WO | disclosed |
| CN-1307565-A | Quinolones used as MRS inhibitor and bactericides | SMITHKLINE BEECHAM PLC (GB) | 2001-08-08 | — | — | CN | disclosed |
| EP-1027332-A1 | NOVEL LACTAM METALLOPROTEASE INHIBITORS | Du Pont Pharmaceuticals Company (US) | 2000-08-16 | — | — | EP | disclosed |
| WO-1999018074-A1 | NOVEL LACTAM METALLOPROTEASE INHIBITORS | Britol-Myers Squibb Pharma Company (US) | 1999-04-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230183226-A1 | AKT3 MODULATORS | AKT3, AKT2, MTOR | LOXL2 2173/4885SMN1; SMN2 2070/4885SYK 1886/4885 |
| US-20090099220-A1 | ANTIMALARIAL COMPOUNDS WITH FLEXIBLE SIDE-CHAINS | DHFR, FPGS, DHODH | LOXL2 3320/4885SMN1; SMN2 3901/4885SYK 1698/4885 |
| US-20100010224-A1 | PROCESS FOR PRODUCTION OF HETEROARYL-TYPE BORON COMPOUNDS WITH IRIDIUM CATALYST | PIN4, IPO5, HLCS | LOXL2 3016/4885SMN1; SMN2 4478/4885SYK 2792/4885 |
| US-20050148775-A1 | Process for production of heteroaryl-type boron compounds with iridium catalyst | PIN4, IPO5, HLCS | LOXL2 3016/4885SMN1; SMN2 4478/4885SYK 2792/4885 |
| US-11780849-B2 | Imino sulfanone inhibitors of ENPP1 | ENPP1, ENPP3, SMPD1 | LOXL2 1956/4885SMN1; SMN2 820/4885SYK 1261/4885 |
| US-10023538-B2 | Compounds, compositions and associated methods comprising 3-aryl quinolines | CYP3A43, ABL1, CYP3A7 | LOXL2 3516/4885SMN1; SMN2 2783/4885SYK 1836/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.