Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 2/20 | 0.44 |
| ▸ | TAOK1 | Q7L7X3 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | F2 | P00734 | 2/20 | 0.36 |
| ▸ | F10 | P00742 | 1/20 | 0.36 |
| ▸ | PLG | P00747 | 1/20 | 0.36 |
| ▸ | PLAU | P00749 | 1/20 | 0.36 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5269257 | 0.82 | CYP1A2 (0.41) | HTR6TAOK1KDM4EGAAHPGD | |
| SCHEMBL5271876 | 0.82 | MTNR1A (0.43) | HTR6TAOK1GAAATMALDH1A1 | |
| SCHEMBL5270515 | 0.81 | EPHX1 (0.46) | HTR6MAPTKDM4EHPGDPOLB | |
| SCHEMBL5271696 | 0.80 | MEN1 (0.41) | HTR6TAOK1MAPTKDM4EHPGD | |
| SCHEMBL5266632 | 0.80 | CASP1 (0.42) | MAPTKDM4EGAARAB9ASMN1; SMN2 | |
| SCHEMBL5269236 | 0.77 | MMP2 (0.41) | HPGDLMNARAB9AALDH1A1MEN1 | |
| SCHEMBL5267069 | 0.76 | ALDH1A1 (0.39) | MAPTKDM4EGAAHPGDSMN1; SMN2 | |
| SCHEMBL5271053 | 0.74 | L3MBTL1 (0.51) | GAAHPGDPOLBLMNAHSD17B10 | |
| SCHEMBL5273212 | 0.73 | ALDH1A1 (0.47) | MAPTGAAF10POLBLMNA | |
| SCHEMBL5273232 | 0.72 | L3MBTL1 (0.36) | HPGDNPC1RAB9AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1847531-A1 | PYRAZOLE COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2007-10-24 | — | — | EP | disclosed |