Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA5 | P22460 | 1/20 | 0.47 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | USP8 | P40818 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | EDNRA | P25101 | 3/20 | 0.43 |
| ▸ | EDNRB | P24530 | 2/20 | 0.43 |
| ▸ | SLC16A3 | O15427 | 4/20 | 0.43 |
| ▸ | PGR | P06401 | 1/20 | 0.43 |
| ▸ | PGAM1 | P18669 | 1/20 | 0.42 |
| ▸ | PLK1 | P53350 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | PFKFB3 | Q16875 | 1/20 | 0.41 |
| ▸ | ACLY | P53396 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5270919 | 0.89 | KCNA5 (0.51) | KCNA5HCRTR1TSHRUSP2USP8 | |
| SCHEMBL5273547 | 0.86 | TSHR (0.49) | KCNA5HCRTR1TSHRUSP2USP8 | |
| SCHEMBL5265874 | 0.84 | SLC16A3 (0.48) | KCNA5HCRTR1TSHRMEN1KMT2A | |
| SCHEMBL5267782 | 0.83 | GAA (0.55) | KCNA5TSHRMEN1KMT2AALDH1A1 | |
| SCHEMBL5268784 | 0.83 | NPC1 (0.47) | KCNA5TSHRMEN1KMT2AALDH1A1 | |
| SCHEMBL5268725 | 0.82 | RAB9A (0.51) | KCNA5TSHRMEN1KMT2ASLC16A3 | |
| SCHEMBL5318573 | 0.80 | SLC40A1 (0.49) | KCNA5TSHRMEN1KMT2AALDH1A1 | |
| SCHEMBL5268835 | 0.80 | HPGD (0.52) | TSHRMEN1KMT2AALDH1A1HTT | |
| SCHEMBL5271876 | 0.79 | MTNR1A (0.43) | PGRPLK1ALDH1A1 | |
| SCHEMBL5269789 | 0.79 | MEN1 (0.51) | TSHRMEN1KMT2APGRPGAM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1847531-A1 | PYRAZOLE COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2007-10-24 | — | — | EP | disclosed |