Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNK3 | O14649 | 1/20 | 0.39 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | PGAM1 | P18669 | 1/20 | 0.37 |
| ▸ | BRAF | P15056 | 1/20 | 0.37 |
| ▸ | MRGPRX1 | Q96LB2 | 1/20 | 0.37 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.36 |
| ▸ | CCR4 | P51679 | 1/20 | 0.36 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5270110 | 0.87 | KCNK3 (0.42) | KCNK3KCNK9HPGDLMNABRD4 | |
| SCHEMBL5265937 | 0.83 | CCNE2 (0.45) | KCNK3KCNK9KDM4EALDH1A1MAPT | |
| SCHEMBL5268756 | 0.82 | LMNA (0.42) | LMNAALDH1A1 | |
| SCHEMBL5267465 | 0.81 | AR (0.43) | KCNK3KCNK9GAAALDH1A1MAPT | |
| SCHEMBL5267869 | 0.80 | RAB9A (0.47) | KCNK3KCNK9HPGDGAAKDM4E | |
| SCHEMBL5267069 | 0.79 | ALDH1A1 (0.39) | KCNK3KCNK9HPGDBRD4GAA | |
| SCHEMBL5269803 | 0.78 | HPGD (0.48) | HPGDLMNAALDH1A1MAPT | |
| SCHEMBL5271876 | 0.75 | MTNR1A (0.43) | GAAALDH1A1 | |
| SCHEMBL13816862 | 0.73 | YTHDC1 (0.41) | HPGDBRD4KDM4E | |
| SCHEMBL5318573 | 0.72 | SLC40A1 (0.49) | HPGDLMNAGAAKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1847531-A1 | PYRAZOLE COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2007-10-24 | — | — | EP | disclosed |