Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5267751 | 0.88 | NPC1 (0.56) | HPGDL3MBTL1GAAMAPTNPC1 | |
| SCHEMBL5271765 | 0.88 | ALDH1A1 (0.48) | RXFP1HPGDL3MBTL1PKMMAPT | |
| SCHEMBL5274022 | 0.88 | L3MBTL1 (0.46) | RXFP1POLBL3MBTL1HTTGAA | |
| SCHEMBL5271053 | 0.88 | L3MBTL1 (0.51) | RXFP1POLBHPGDL3MBTL1GAA | |
| SCHEMBL5268091 | 0.86 | LMNA (0.55) | POLBHPGDL3MBTL1GAAMAPT | |
| SCHEMBL5269971 | 0.86 | L3MBTL1 (0.50) | RXFP1POLBHPGDL3MBTL1HTT | |
| SCHEMBL5265743 | 0.84 | ALDH1A1 (0.53) | POLBL3MBTL1HTTGAAMAPT | |
| SCHEMBL5273212 | 0.82 | ALDH1A1 (0.47) | RXFP1POLBL3MBTL1HTTGAA | |
| SCHEMBL5273232 | 0.79 | L3MBTL1 (0.36) | HPGDL3MBTL1NPC1RAB9A | |
| SCHEMBL5268738 | 0.79 | METAP2 (0.44) | POLBHPGDL3MBTL1HTTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1847531-A1 | PYRAZOLE COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2007-10-24 | — | — | EP | disclosed |