Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | RECQL | P46063 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | MPI | P34949 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | CASP6 | P55212 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | PLEC | Q15149 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5272425 | 0.87 | MAOA (0.42) | MAPTALDH1A1KMT2AL3MBTL1ALOX12 | |
| SCHEMBL5272368 | 0.87 | BCHE (0.47) | MAPTALDH1A1KMT2ALMNARECQL | |
| SCHEMBL5271190 | 0.86 | MAPT (0.37) | MAPTALDH1A1KMT2AALOX12MEN1 | |
| SCHEMBL5270890 | 0.85 | HIF1A (0.44) | MAPTALDH1A1ALOX12MAOBCA12 | |
| SCHEMBL5272106 | 0.84 | KDM4E (0.46) | MAPTALDH1A1KMT2ALMNATDP1 | |
| SCHEMBL5274977 | 0.84 | AGER (0.47) | MAPTALDH1A1KMT2ARECQLTDP1 | |
| SCHEMBL5272301 | 0.84 | MAPT (0.57) | MAPTALDH1A1KMT2ATDP1L3MBTL1 | |
| SCHEMBL5270148 | 0.84 | ACHE (0.42) | MAPTALDH1A1KMT2ARECQLL3MBTL1 | |
| SCHEMBL5272458 | 0.83 | BRD4 (0.45) | MAPTALDH1A1KMT2AMEN1RAB9A | |
| SCHEMBL5269215 | 0.81 | ARG1 (0.41) | MAPTALDH1A1KMT2AALOX12KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1846361-A2 | 3-AMINO-2-AMINOMETHYLPHENOL DERIVATIVES AND COLORANTS COMPRISING THESE COMPOUNDS | Wella Aktiengesellschaft (DE) | 2007-10-24 | — | — | EP | claimed |
| US-20070022546-A1 | 3-Amino-2-aminomethylphenol derivatives and colorants comprising these compounds | PROCTER & GAMBLE COMPANY, THE | 2007-02-01 | — | — | US | claimed |
| WO-2006086374-A2 | 3-AMINO-2-AMINOMETHYLPHENOL DERIVATIVES AND COLORANTS COMPRISING THESE COMPOUNDS | THE PROCTER & GAMBLE COMPANY (US) | 2006-08-17 | — | — | WO | claimed |
| EP-1846361-A2 | 3-AMINO-2-AMINOMETHYLPHENOL DERIVATIVES AND COLORANTS COMPRISING THESE COMPOUNDS | Wella Aktiengesellschaft (DE) | 2007-10-24 | — | — | EP | disclosed |
| US-20070022546-A1 | 3-Amino-2-aminomethylphenol derivatives and colorants comprising these compounds | PROCTER & GAMBLE COMPANY, THE | 2007-02-01 | — | — | US | disclosed |
| WO-2006086374-A2 | 3-AMINO-2-AMINOMETHYLPHENOL DERIVATIVES AND COLORANTS COMPRISING THESE COMPOUNDS | THE PROCTER & GAMBLE COMPANY (US) | 2006-08-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070022546-A1 | 3-Amino-2-aminomethylphenol derivatives and colorants comprising these compounds | KRT18, COL2A1, COL1A1 | MAPT 317/4885ALDH1A1 402/4885KMT2A 679/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.