Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 10/20 | 0.64 |
| ▸ | KYNU | Q16719 | 1/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.61 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.61 |
| ▸ | CTSS | P25774 | 5/20 | 0.60 |
| ▸ | CTSL | P07711 | 4/20 | 0.60 |
| ▸ | CTSB | P07858 | 3/20 | 0.60 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.57 |
| ▸ | TACR1 | P25103 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4387860 | 1.00 | CTSK (0.64) | CTSKKYNUALDH1A1ALOX15CTSS | |
| SCHEMBL527104 | 1.00 | CTSK (0.64) | CTSKKYNUALDH1A1ALOX15CTSS | |
| SCHEMBL1643831 | 0.91 | CTSK (0.60) | CTSKKYNUALDH1A1ALOX15CTSS | |
| SCHEMBL1643830 | 0.91 | CTSK (0.60) | CTSKKYNUALDH1A1ALOX15CTSS | |
| SCHEMBL526571 | 0.91 | CTSK (0.60) | CTSKKYNUALDH1A1ALOX15CTSS | |
| SCHEMBL28162782 | 0.91 | KYNU (0.60) | CTSKKYNUALDH1A1ALOX15CTSS | |
| SCHEMBL5191992 | 0.91 | KYNU (0.60) | CTSKKYNUALDH1A1ALOX15CTSS | |
| SCHEMBL16351361 | 0.90 | KYNU (0.62) | CTSKKYNUALDH1A1ALOX15CTSS | |
| SCHEMBL18075229 | 0.89 | CTSK (0.65) | CTSKCTSSCTSLCTSBCAPN1 | |
| SCHEMBL18075231 | 0.89 | CTSK (0.65) | CTSKCTSSCTSLCTSBCAPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118530297-A | Ketone amide compound, preparation method and application thereof | 四川大学 | 2024-08-23 | — | — | CN | disclosed |
| EP-3144295-A1 | PROCESS FOR THE PREPARATION OF LACOSAMIDE | Divi's Laboratories Limited (IN) | 2017-03-22 | — | — | EP | disclosed |
| US-9447024-B1 | Process for the preparation of lacosamide | DIVI'S LABORATORIES LIMITED (IN) | 2016-09-20 | — | — | US | disclosed |
| US-9447024-B1 | Process for the preparation of lacosamide | DIVI'S LABORATORIES LIMITED (IN) | 2016-09-20 | — | — | US | disclosed |
| WO-2015042397-A1 | GLUCOSYLCERAMIDE SYNTHASE INHIBITORS FOR THE TREATMENT OF DISEASES | BIOMARIN PHARMACEUTICAL INC. (US) | 2015-03-26 | — | — | WO | disclosed |
| US-8957252-B2 | Process for preparation of lacosamide and some N-benzyl-propanamide intermediate derivatives | INDOCO REMEDIES LIMITED (IN) | 2015-02-17 | — | — | US | disclosed |
| US-8957252-B2 | Process for preparation of lacosamide and some N-benzyl-propanamide intermediate derivatives | INDOCO REMEDIES LIMITED (IN) | 2015-02-17 | — | — | US | disclosed |
| US-8957252-B2 | Process for preparation of lacosamide and some N-benzyl-propanamide intermediate derivatives | INDOCO REMEDIES LIMITED (IN) | 2015-02-17 | — | — | US | disclosed |
| US-8829226-B2 | Lacosamide intermediate compound, preparation method thereof and use thereof | ZHEJIANG JIUZHOU PHARMACEUTICAL CO., LTD (CN) | 2014-09-09 | — | — | US | disclosed |
| EP-2598476-B1 | PROCESS FOR PREPARATION OF LACOSAMIDE AND SOME N-BENZYL-PROPANAMIDE INTERMEDIATE DERIVATIVES | INDOCO REMEDIES LTD (IN) | 2014-07-02 | — | — | EP | disclosed |
| US-20130123537-A1 | PROCESS FOR THE PREPARATION OF LACOSAMIDE | AUROBINDO PHARMA LTD. (IN) | 2013-05-16 | — | — | US | disclosed |
| US-20130123522-A1 | PROCESS FOR PREPARATION OF LACOSAMIDE AND SOME N-BENZYL-PROPANAMIDE INTERMEDIATE DERIVATIVES | INDOCO REMEDIES LIMITED (IN) | 2013-05-16 | — | — | US | disclosed |
| US-20130123522-A1 | PROCESS FOR PREPARATION OF LACOSAMIDE AND SOME N-BENZYL-PROPANAMIDE INTERMEDIATE DERIVATIVES | INDOCO REMEDIES LIMITED (IN) | 2013-05-16 | — | — | US | disclosed |
| US-20130102811-A1 | PROCESS FOR THE PREPARATION OF LACOSAMIDE | SUN PHARMACEUTICAL INDUSTRIES LTD (IN) | 2013-04-25 | — | — | US | disclosed |
| US-20130066102-A1 | LACOSAMIDE INTERMEDIATE COMPOUND, PREPARATION METHOD THEREOF AND USE THEREOF | ZHEJIANG JIUZHOU PHARMACEUTICAL CO., LTD (CN) | 2013-03-14 | — | — | US | disclosed |
| US-20130035508-A1 | PROCESS FOR THE PREPARATION OF LACOSAMIDE | NATCO PHARMA LIMITED (IN) | 2013-02-07 | — | — | US | disclosed |
| US-20120283466-A1 | LACOSAMIDE INTERMEDIATE COMPOUND, PREPARATION METHOD THEREOF AND USE THEREOF | ZHEJIANG JIUZHOU PHARMACEUTICAL CO., LTD. (CN) | 2012-11-08 | — | — | US | disclosed |
| US-20120283466-A1 | LACOSAMIDE INTERMEDIATE COMPOUND, PREPARATION METHOD THEREOF AND USE THEREOF | ZHEJIANG JIUZHOU PHARMACEUTICAL CO., LTD. (CN) | 2012-11-08 | — | — | US | disclosed |
| WO-2012014226-A1 | PROCESS FOR PREPARATION OF LACOSAMIDE AND SOME N-BENZYL-PROPANAMIDE INTERMEDIATE DERIVATIVES | INDOCO REMEDIES LIMITED (IN) | 2012-02-02 | — | — | WO | disclosed |
| WO-2011095995-A1 | A PROCESS FOR THE PREPARATION OF LACOSAMIDE | NATCO PHARMA LIMITED (IN) | 2011-08-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130035508-A1 | PROCESS FOR THE PREPARATION OF LACOSAMIDE | CA3, CACNA1A, CA2 | CTSK 1891/4885KYNU 107/4885ALDH1A1 1559/4885 |
| US-20130102811-A1 | PROCESS FOR THE PREPARATION OF LACOSAMIDE | SLC6A11, CACNA1B, SLC6A1 | CTSK 932/4885KYNU 30/4885ALDH1A1 1393/4885 |
| US-20130066102-A1 | LACOSAMIDE INTERMEDIATE COMPOUND, PREPARATION METHOD THEREOF AND USE THEREOF | IDH3A, CACNA1C, DDC | CTSK 1040/4885KYNU 33/4885ALDH1A1 1017/4885 |
| US-20130123522-A1 | PROCESS FOR PREPARATION OF LACOSAMIDE AND SOME N-BENZYL-PROPANAMIDE INTERMEDIATE DERIVATIVES | LPXN, CACNA1B, PMP22 | CTSK 2162/4885KYNU 120/4885ALDH1A1 1121/4885 |
| US-20130123537-A1 | PROCESS FOR THE PREPARATION OF LACOSAMIDE | MYT1, TET1, LPXN | CTSK 2691/4885KYNU 38/4885ALDH1A1 2151/4885 |
| US-20120283466-A1 | LACOSAMIDE INTERMEDIATE COMPOUND, PREPARATION METHOD THEREOF AND USE THEREOF | IDH3A, CACNA1C, DDC | CTSK 1040/4885KYNU 33/4885ALDH1A1 1017/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.