Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.58 |
| ▸ | MAPT | P10636 | 4/20 | 0.58 |
| ▸ | HTT | P42858 | 3/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | NPC1 | O15118 | 3/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | AHR | P35869 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL528487 | 0.90 | MAPT (0.46) | ALDH1A1MAPTHTTNPSR1GAA | |
| SCHEMBL528938 | 0.89 | ALDH1A1 (0.59) | ALDH1A1MAPTHTTNPSR1GAA | |
| SCHEMBL528626 | 0.86 | ALDH1A1 (0.46) | ALDH1A1MAPTHTTNPSR1GAA | |
| SCHEMBL528276 | 0.86 | ROCK2 (0.51) | ALDH1A1MAPTHTTGAANPC1 | |
| SCHEMBL528937 | 0.86 | MAPT (0.47) | ALDH1A1MAPTHTTNPSR1GAA | |
| SCHEMBL528053 | 0.85 | MAPT (0.55) | ALDH1A1MAPTHTTNPSR1GAA | |
| SCHEMBL528401 | 0.85 | MAPT (0.47) | ALDH1A1MAPTHTTNPSR1GAA | |
| SCHEMBL528292 | 0.84 | TP53 (0.46) | ALDH1A1MAPTHTTNPSR1GAA | |
| SCHEMBL528514 | 0.84 | L3MBTL1 (0.49) | ALDH1A1MAPTHTTNPC1POLB | |
| SCHEMBL528578 | 0.81 | ROCK2 (0.53) | ALDH1A1MAPTHTTGAANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012014127-A1 | 5-LIPOXYGENASE INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2012-02-02 | — | — | WO | disclosed |