Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.35 |
| ▸ | IGLV6-57 | P01721 | 1/20 | 0.33 |
| ▸ | DAO | P14920 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4064736 | 0.78 | HTR7 (0.44) | ALDH1A1 | |
| SCHEMBL19960904 | 0.77 | S100B (0.43) | KDM4EALDH1A1 | |
| SCHEMBL1433223 | 0.75 | ADRA2A (0.48) | ADRA2AADRA2BADRA2CIGLV6-57KDM4E | |
| SCHEMBL21201333 | 0.73 | ALDH1A1 (0.42) | KDM4EALDH1A1 | |
| SCHEMBL19960884 | 0.72 | S100B (0.43) | KDM4EALDH1A1 | |
| SCHEMBL28233363 | 0.72 | IGLV6-57 (0.37) | ADRA2AADRA2BADRA2CIGLV6-57DAO | |
| SCHEMBL16682949 | 0.71 | ADRA2A (0.46) | ADRA2AADRA2BADRA2CIGLV6-57KDM4E | |
| SCHEMBL10000460 | 0.70 | LMNA (0.45) | ADRA2AADRA2BADRA2CIGLV6-57KDM4E | |
| SCHEMBL5282620 | 0.70 | ADRA2A (0.35) | ADRA2AADRA2BADRA2CIGLV6-57DAO | |
| SCHEMBL5281677 | 0.70 | TSHR (0.40) | ADRA2AADRA2BADRA2CIGLV6-57DAO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006103342-A9 | INDANYL-PIPERAZINE DERIVATIVES, METHOD FOR PREPARING SAME AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | SERVIER LAB (FR) | 2007-10-25 | — | — | WO | disclosed |
| WO-2006103342-A2 | INDANYL-PIPERAZINE DERIVATIVES, METHOD FOR PREPARING SAME AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | LES LABORATOIRES SERVIER (FR) | 2006-10-05 | — | — | WO | disclosed |